SCHEMBL484558

SCHEMBL484558

C=CCOC(=O)C1=CCC(=O)C=C1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.45
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 2/20 0.40
TSHR P16473 1/20 0.40
SNCA P37840 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
RHOA P61586 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3110549 0.81 SERPINE1 (0.37) TSHR
SCHEMBL10855434 0.79 CYP3A4 (0.41) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL10850059 0.77 CYP3A4 (0.39) CYP3A4ALDH1A1HSD17B10TSHRSNCA
SCHEMBL1435298 0.75 ALDH1A1 (0.46) CYP3A4ALDH1A1TSHRMEN1KMT2A
SCHEMBL598039 0.74 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRKDM4EHPGD
Water SCHEMBL7768611 0.71 DHFR (0.38) CYP3A4ALDH1A1TP53
SCHEMBL9312179 0.71 ALDH1A1 (0.49) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL659382 0.71 ALDH1A1 (0.49) CYP3A4ALDH1A1HSD17B10TSHRKDM4E
SCHEMBL7035636 0.70 LMNA (0.36) ALDH1A1TSHRCA1CA2KDM4E
SCHEMBL3205528 0.69 ALDH1A1 (0.32) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024138379-A1 USE OF COATING SYSTEM COMPRISING ACRYLIC PRE-COAT AND SILICONE TOP-COAT IN A PAPER-BASED FOOD CONTAINER AND THE PAPER-BASED FOOD CONTAINER COATED WITH THE COATING SYSTEM ELKEM SILICONES SHANGHAI CO., LTD. (CN) 2024-07-04 WO disclosed
EP-3449904-B1 EMULSIFIED COSMETIC SHINETSU CHEMICAL CO (JP) 2024-06-19 EP disclosed
EP-4368660-A1 CROSSLINKED ORGANIC SILICON RESIN, METHOD FOR PRODUCING SAME, AND COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-15 EP disclosed
EP-4310151-A1 AQUEOUS DISPERSION OF SILICONE RUBBER PARTICLES, AND COSMETIC PREPARATION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-24 EP disclosed
EP-3900700-B1 MICROEMULSION COMPOSITION, CURED PRODUCT THEREOF, AND COSMETIC MATERIAL CONTAINING SAME SHINETSU CHEMICAL CO (JP) 2023-09-13 EP disclosed
EP-3493681-B1 STABILIZED EMULSIONS SUNCOR ENERGY INC (CA) 2023-08-30 EP disclosed
US-20230263720-A1 COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-24 US disclosed
US-20230233424-A1 USE OF A MINERAL BLEND AS COSMETIC AGENT FOR WET COSMETIC COMPOSITIONS OMYA INTERNATIONAL AG (CH) 2023-07-27 US disclosed
US-20230149290-A1 MICROEMULSION COMPOSITION AND COSMETIC CONTAINING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-18 US disclosed
EP-4157202-A1 USE OF A MINERAL BLEND AS COSMETIC AGENT FOR WET COSMETIC COMPOSITIONS Omya International AG (CH) 2023-04-05 EP disclosed
EP-0455018-B1 Pigment consisting of polyvalent metal salt of amidosulfonic acid and cosmetic composition containing the same KAO CORP (JP) 1994-09-07 EP disclosed
US-5340582-A Crystal structure, optical characteristics KAO CORPORATION (JP) 1994-08-23 US disclosed
US-5262148-A HEATING A BARIUM SALT AND A SULFATE UNDER ACIDIC CONDITIONS TO REACT, FORMING BARIUM SULFATE HAVING A PLATE CRYSTAL STRUCTURE KAO CORPORATION (JP) 1993-11-16 US disclosed
US-5171572-A BARIUM SULFATE AND COSMETIC COMPOSITIONS COMPRISING SAME KAO CORPORATION (JP) 1992-12-15 US disclosed
US-5167709-A Improved spreadability KAO CORPORATION (JP) 1992-12-01 US disclosed
EP-0201040-B1 COSMETICS COMPRISING AN OIL-GELLING AGENT Kao Corporation (JP) 1991-11-13 EP disclosed
EP-0455018-A1 Pigment consisting of polyvalent metal salt of amidosulfonic acid and cosmetic composition containing the same KAO CORPORATION (JP) 1991-11-06 EP disclosed
EP-0445785-A1 Plate-like barium sulfate and cosmetic composition KAO CORPORATION (JP) 1991-09-11 EP disclosed
US-4791140-A GELATION WITH METAL SALT OF DIALKYL PHOSPHATE KAO CORPORATION (JP) 1988-12-13 US disclosed
EP-0201040-A2 Cosmetics comprising an oil-gelling agent Kao Corporation (JP) 1986-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149290-A1 MICROEMULSION COMPOSITION AND COSMETIC CONTAINING THE SAME MAN2B1, MGLL, LIPA CYP3A4 3814/4885ALDH1A1 1388/4885HSD17B10 672/4885
US-20230263720-A1 COSMETIC ALG1, ALG3, CUTA CYP3A4 2191/4885ALDH1A1 28/4885HSD17B10 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.