Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274480 | 0.89 | PREP (0.43) | PREPATMCTSKCTSLCTSB | |
| SCHEMBL5636335 | 0.83 | HTR2A (0.53) | ATMCTSKMEN1KMT2AHTR1A | |
| SCHEMBL5050630 | 0.83 | HTR2A (0.53) | ATMCTSKMEN1KMT2AHTR1A | |
| SCHEMBL17357685 | 0.79 | CTSL (0.53) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL7009702 | 0.77 | KMO (0.44) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL4779482 | 0.73 | MCHR1 (0.47) | ATMCTSKCTSSHTR2AHTR2C | |
| SCHEMBL5055858 | 0.73 | MCHR1 (0.47) | ATMCTSKCTSSHTR2AHTR2C | |
| SCHEMBL6359649 | 0.73 | HTR2A (0.54) | ATMCTSKCTSLCTSSMEN1 | |
| SCHEMBL8206098 | 0.72 | PREP (0.61) | PREPATMCTSKCTSLCTSB | |
| SCHEMBL11254461 | 0.72 | PREP (0.61) | PREPATMCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080033184-A1 | INTERMEDIATES AND METHODS FOR SEROTONERGIC AGONIST SYNTHESIS | ALCON MANUFACTURING, LTD. (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080033184-A1 | INTERMEDIATES AND METHODS FOR SEROTONERGIC AGONIST SYNTHESIS | ALCON MANUFACTURING, LTD. (US) | 2008-02-07 | — | — | US | disclosed |
| WO-2008016993-A1 | INTERMEDIATES AND METHODS FOR SEROTONERGIC AGONIST SYNTHESIS | ALCON RESEARCH, LTD. (US) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008016993-A1 | INTERMEDIATES AND METHODS FOR SEROTONERGIC AGONIST SYNTHESIS | ALCON RESEARCH, LTD. (US) | 2008-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033184-A1 | INTERMEDIATES AND METHODS FOR SEROTONERGIC AGONIST SYNTHESIS | HTR3B, HTR3A, HTR4 | PREP 2012/4885ATM 3514/4885CTSK 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.