Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 3/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846834 | 0.84 | ROCK2 (0.50) | CCNA2CDK2CCNA1HDAC1HDAC8 | |
| SCHEMBL16422794 | 0.84 | FPR2 (0.48) | CCNA2CDK2CCNA1GFERMAPT | |
| SCHEMBL18048847 | 0.84 | ROCK2 (0.50) | CCNA2CDK2CCNA1HDAC1HDAC8 | |
| SCHEMBL18048717 | 0.84 | ROCK2 (0.50) | CCNA2CDK2CCNA1HDAC1HDAC8 | |
| SCHEMBL826237 | 0.83 | MEN1 (0.50) | DDB1CRBNHDAC1HDAC8HDAC6 | |
| SCHEMBL826412 | 0.83 | MEN1 (0.50) | DDB1CRBNHDAC1HDAC8HDAC6 | |
| SCHEMBL3083319 | 0.83 | MEN1 (0.50) | DDB1CRBNHDAC1HDAC8HDAC6 | |
| SCHEMBL2735075 | 0.82 | CA1 (0.54) | ALDH1A1KDM4EPOLBLMNATDP1 | |
| SCHEMBL13846075 | 0.81 | CCNA2 (0.39) | DDB1CRBNCCNA2CDK2CCNA1 | |
| SCHEMBL4573116 | 0.80 | CCNA2 (0.38) | DDB1CRBNCCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7429278-B2 | N-alkyleheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'ORÉAL (FR) | 2008-09-30 | — | — | US | disclosed |
| US-7422609-B2 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | L'OREAL S.A. | 2008-03-20 | — | — | US | disclosed |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20060005320-A1 | N-alkylheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011828-A1 | Novel double para-phenylenediamines joined by a branched aliphatic group and method of dyeing keratin fibers | KRT18, CDC73, DSP | DDB1 87/4885CRBN 1066/4885CCNA2 2017/4885 |
| US-20070011829-A1 | Novel double para-phenylenediamines joined by a linkage comprising an atom chosen from sulphur and nitrogen and method for dyeing keratinous fibers | KRT18, DSP, CDC73 | DDB1 271/4885CRBN 564/4885CCNA2 2653/4885 |
| US-20080069789-A1 | N-ALKYLHETEROARYL SECONDARY PARA-PHENYLENEDIAMINE AND COMPOSITION COMPRISING SUCH A PARA-PHENYLENEDIAMINE | KRT18, CDC73, PRKDC | DDB1 463/4885CRBN 739/4885CCNA2 1414/4885 |
| US-20070011824-A1 | Double para-phenylenediamines joined by an aromatic group for dyeing keratin fibers | KRT18, CDC73, JUP | DDB1 139/4885CRBN 563/4885CCNA2 1945/4885 |
| US-20060005320-A1 | N-alkylheteroaryl secondary para-phenylenediamine and composition comprising such a para-phenylenediamine | KRT18, CDC73, PRKDC | DDB1 463/4885CRBN 739/4885CCNA2 1414/4885 |
| US-20070011825-A1 | Novel double para-phenylenediamines joined by a linkage comprising a saturated cyclic radical and use in dyeing | KRT18, CDC73, AOC1 | DDB1 190/4885CRBN 979/4885CCNA2 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.