Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | FPR1 | P21462 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083319 | 1.00 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL826412 | 1.00 | MEN1 (0.50) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL3984910 | 0.89 | KMT2A (0.47) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL4847013 | 0.83 | DDB1 (0.43) | MEN1KMT2ANPC1RAB9ADDB1 | |
| SCHEMBL18048717 | 0.81 | ROCK2 (0.50) | MEN1KMT2AHDAC8HDAC6HDAC1 | |
| SCHEMBL16422794 | 0.81 | FPR2 (0.48) | MEN1KMT2ARAB9AFPR2ROCK2 | |
| SCHEMBL5846834 | 0.81 | ROCK2 (0.50) | MEN1KMT2AHDAC8HDAC6HDAC1 | |
| SCHEMBL4573116 | 0.81 | CCNA2 (0.38) | DDB1CRBNHDAC8HDAC6HDAC1 | |
| SCHEMBL18048847 | 0.81 | ROCK2 (0.50) | MEN1KMT2AHDAC8HDAC6HDAC1 | |
| SCHEMBL11066860 | 0.81 | NPC1 (0.47) | MEN1KMT2ANPC1RAB9ADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4717317-A2 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 Therapeutics, Inc. (US) | 2026-04-01 | — | — | EP | disclosed |
| EP-3641762-B1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS INC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20260015362-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| US-12441740-B2 | N/O-linked degrons and degronimers for protein degradation | C4 THERAPEUTICS, INC. (US) | 2025-10-14 | — | — | US | disclosed |
| US-20250101037-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2025-03-27 | — | — | US | disclosed |
| US-12180225-B2 | N/O-linked degrons and degronimers for protein degradation | C4 THERAPEUTICS, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| CN-118440096-A | Degradation stator and degradation determinant for N/O-ligation of protein degradation | C4医药公司 | 2024-08-06 | — | — | CN | disclosed |
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| WO-2009064752-A2 | HETEROCYCLIC DERIVATIVES AS MODULATORS OF ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009064747-A2 | 4(-3-(-2-(PHENYL)MORPHOLINO)-2-OXOPYRROLIDIN-1-YL)-N-(THIAZOL-2-YL)BENZENESULFONAMIDE DERIVATI VES AND RELATED COMPOUNDS AS MODULATORS OF ION CHANNELS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20090012055-A1 | Organic compounds | HEROLD PETER | 2009-01-08 | — | — | US | disclosed |
| EP-1961752-A2 | Piperidine Compounds | Speedel Experimenta AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-20070010511-A1 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1670760-A1 | ORGANIC COMPOUNDS | Speedel Experimenta AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |
| US-20030171218-A1 | Substituted 3-heteroaryl(amino- or oxy)pyrrolidin-2-ones, their preparation and use as herbicides or plant growth regulators | BAYER CROPSCIENCE GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
| WO-2003005824-A2 | SUBSTITUTED 3-HETEROARYL (AMINO-OR-OXY)-PYRROLIDIN-2-ONES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES OR AS PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-01-23 | — | — | WO | disclosed |
| CN-1095066-A | Weedicide | ZENECA LTD (GB) | 1994-11-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12441740-B2 | N/O-linked degrons and degronimers for protein degradation | CRBN, CBL, STUB1 | MEN1 562/4885KMT2A 1996/4885NPC1 2599/4885 |
| US-20250101037-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | CRBN, CBL, STUB1 | MEN1 562/4885KMT2A 1996/4885NPC1 2599/4885 |
| US-20090012055-A1 | Organic compounds | REN, ACE, ACE2 | MEN1 2817/4885KMT2A 3839/4885NPC1 794/4885 |
| US-12180225-B2 | N/O-linked degrons and degronimers for protein degradation | CRBN, CBL, STUB1 | MEN1 562/4885KMT2A 1996/4885NPC1 2599/4885 |
| US-20070010511-A1 | Organic compounds | REN, ACE, ACE2 | MEN1 2817/4885KMT2A 3839/4885NPC1 794/4885 |
| US-20260015362-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | CRBN, CBLC, CBL | MEN1 660/4885KMT2A 2401/4885NPC1 998/4885 |
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | CRBN, CBL, STUB1 | MEN1 562/4885KMT2A 1996/4885NPC1 2599/4885 |
| US-20030171218-A1 | Substituted 3-heteroaryl(amino- or oxy)pyrrolidin-2-ones, their preparation and use as herbicides or plant growth regulators | DDT, OXGR1, OGDH | MEN1 4725/4885KMT2A 1000/4885NPC1 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.