SCHEMBL4847240

SCHEMBL4847240

Cl[Si](Cl)(Cl)c1ccccc1CBr

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 1/20 0.35
PNMT P11086 1/20 0.34
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31
BLM P54132 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL937353 0.78 ALDH1A1 (0.39) TSHRALDH1A1PNMTIDO1
SCHEMBL8970526 0.76 MGAM (0.37) TSHRTRPA1ALDH1A1PNMTCYP1A2
SCHEMBL4841457 0.76 PNMT (0.34) PNMTIDO1
SCHEMBL10709160 0.76 GABRA1 (0.41) ALDH1A1PNMTCYP2D6
SCHEMBL18796272 0.76 TSHR (0.35) TSHRTRPA1ALDH1A1PNMTCYP1A2
SCHEMBL2524726 0.76 IDO1 (0.50) PNMTIDO1
SCHEMBL21195817 0.74 TSHR (0.35) TSHRTRPA1ALDH1A1PNMTCYP1A2
SCHEMBL10708865 0.73 ADRA2B (0.36) ALDH1A1PNMT
SCHEMBL28289 0.73 TSHR (0.50) TSHRTRPA1ALDH1A1PNMTCYP1A2
SCHEMBL29382225 0.73 TSHR (0.50) TSHRTRPA1ALDH1A1PNMTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7463400-B1 Electrochromic display device FUJI XEROX CO., LTD. (JP) 2008-12-09 US disclosed
US-6284365-B1 FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE FUJI XEROX CO., LTD. (JP) 2001-09-04 US disclosed