SCHEMBL4841457

SCHEMBL4841457

Cl[Si](Cl)(Cl)c1ccccc1CI

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.34
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL937353 0.78 ALDH1A1 (0.39) PNMTIDO1
SCHEMBL9715535 0.78 PNMT (0.31) PNMT
SCHEMBL4847240 0.76 TSHR (0.35) PNMTIDO1
SCHEMBL2524726 0.76 IDO1 (0.50) PNMTIDO1
SCHEMBL10709160 0.76 GABRA1 (0.41) PNMT
SCHEMBL21195901 0.76 MGAM (0.37) PNMTIDO1
SCHEMBL10708865 0.73 ADRA2B (0.36) PNMT
SCHEMBL647527 0.73 ALDH1A1 (0.40) PNMTIDO1
SCHEMBL2515485 0.73 TSHR (0.35)
SCHEMBL4079752 0.71 GABRA1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7463400-B1 Electrochromic display device FUJI XEROX CO., LTD. (JP) 2008-12-09 US disclosed
US-6284365-B1 FOR CONTROLLING PHYSICAL PROPERTIES OF SURFACE AND INTERFACE OF SOLID ARTICLE SUCH AS WETTABILITY, ADHESIVE PROPERTY, SURFACE ENERGY, DISPERSABILITY, CHEMICAL RESISTANCE FUJI XEROX CO., LTD. (JP) 2001-09-04 US disclosed