Fluorene

Fluorene

SCHEMBL4847437

CCOCC.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.48
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
GABRA4 P48169 1/20 0.46
GABRE P78334 1/20 0.46
GABRA6 Q16445 1/20 0.46
GABRG1 Q8N1C3 1/20 0.46
GABRG3 Q99928 1/20 0.46
GABRQ Q9UN88 1/20 0.46
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL28253911 0.85 ALDH1A1 (0.50) MAOAGABRPGABRDGABRA1GABRB1
Fluorene SCHEMBL28329249 0.84 ALDH1A1 (0.48) MAOAGABRPGABRDGABRA1GABRB1
Fluorene SCHEMBL28046849 0.84 GABRP (0.49) MAOAGABRPGABRDGABRA1GABRB1
Fluorene SCHEMBL7863457 0.83 MAOA (0.54) MAOAGABRPGABRDGABRA1GABRB1
Fluorene SCHEMBL27641511 0.81 MAOA (0.58) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL27830018 0.81 MAOA (0.58) MAOAALDH1A1NPC1RAB9AKDM4E
Fluorene SCHEMBL275817 0.81 MAOA (0.52) MAOAGABRPGABRDGABRA1GABRB1
Ether SCHEMBL9618978 0.80 PNMT (0.46) GABRPGABRDGABRA1GABRB1GABRG2
Ether SCHEMBL6738747 0.80 PNMT (0.46) MAOAGABRPGABRDGABRA1GABRB1
Fluorene SCHEMBL28255479 0.80 MAOA (0.56) MAOAALDH1A1NPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107851534-A Electrical power distribution switches cabinet and power current cutting-off method ABB瑞士股份有限公司 2018-03-27 CN claimed
CN-110483247-A Metal alkoxides powder and preparation method and application BEIJING GUODA HENGTAI SCIENCE AND TRADE CO LTD 2019-11-22 CN disclosed
CN-107851534-A Electrical power distribution switches cabinet and power current cutting-off method ABB瑞士股份有限公司 2018-03-27 CN disclosed
CN-100539271-C Solid polymer electrolyte membrane and method for producing same ASAHI CHEMICAL CORP (JP) 2009-09-09 CN disclosed
US-RE40234-E1 Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system EXXONMOBIL CHEMICAL PATENTS, INC. 2008-04-08 US disclosed
CN-101015081-A Solid polymer electrolyte membrane and method for producing same ASAHI CHEMICAL CORP (JP) 2007-08-08 CN disclosed
US-7041841-B1 Process for producing crystalline poly-α-olefins with a monocyclopentadienyl transition metal catalyst system EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-09 US disclosed
EP-1565499-A2 POLYOLEFIN PRODUCTION TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2005-08-24 EP disclosed
WO-2004046207-A2 POLYOLEFIN PRODUCTION TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2004-06-03 WO disclosed
US-6617466-B1 Having a heteroatom ligand containing an element with a coordination number of three from Group V A or a coordination number of two from Group VI A attached to the ring through a hydrocarbylene, silane or germanium group EXXONMOBIL CHEMICAL PATENTS INC. 2003-09-09 US disclosed
EP-0643066-A2 Monocyclopentadienyl transition metal olefin polymerization catalysts EXXON CHEMICAL PATENTS INC. (US) 1995-03-15 EP disclosed
EP-0631589-A1 IONIC CATALYST FOR THE PRODUCTION OF POLY-$g(a)-OLEFINS OF CONTROLLED TACTICITY EXXON CHEMICAL PATENTS INC. (US) 1995-01-04 EP disclosed
WO-1993019103-A1 IONIC CATALYST FOR THE PRODUCTION OF POLY-α-OLEFINS OF CONTROLLED TACTICITY EXXON CHEMICAL PATENTS INC. (US) 1993-09-30 WO disclosed
EP-0548277-A1 PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM EXXON CHEMICAL PATENTS INC. (US) 1993-06-30 EP disclosed
EP-0491842-A1 MONOCYCLOPENTADIENYL TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS. EXXON CHEMICAL PATENTS INC (US) 1992-07-01 EP disclosed
WO-1992005204-A1 PROCESS FOR PRODUCING CRYSTALLINE POLY-ALPHA-OLEFINS WITH A MONOCYCLOPENTADIENYL TRANSITION METAL CATALYST SYSTEM EXXON CHEMICAL PATENTS INC. (US) 1992-04-02 WO disclosed
US-5096867-A Polymer products of high molecular weight and narrow molecular weight distribution using small amounts of an alumoxane with the titanium complex EXXON CHEMICAL PATENTS INC. (US) 1992-03-17 US disclosed
US-5026798-A Coordination catalyst EXXON CHEMICAL PATENTS INC. (US) 1991-06-25 US disclosed
WO-1991004257-A1 MONOCYCLOPENTADIENYL TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 1991-04-04 WO disclosed
US-4661297-A ANTILEUKEMIA AGENTS; IMMUNOSUPPRESSIVE AGENTS SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) 1987-04-28 US disclosed