Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219361 | 0.83 | KMT2A (0.39) | ALDH1A1HPGDFAAHPOLBKMT2A | |
| SCHEMBL28413103 | 0.81 | GABRA1 (0.39) | ALDH1A1L3MBTL1GAASMN1; SMN2LMNA | |
| SCHEMBL9868958 | 0.79 | GABRA1 (0.37) | ALDH1A1L3MBTL1GAAMAPTHTT | |
| SCHEMBL1261423 | 0.77 | ACLY (0.41) | ALDH1A1FAAHPOLBKMT2AKDM4E | |
| SCHEMBL8418210 | 0.74 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1HPGDTDP1KMT2A | |
| SCHEMBL13475687 | 0.73 | L3MBTL1 (0.55) | ALDH1A1L3MBTL1POLBTDP1KMT2A | |
| SCHEMBL28410216 | 0.72 | LTB4R (0.40) | TAAR1 | |
| SCHEMBL15173321 | 0.72 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL91337 | 0.71 | KDM4E (0.45) | ALDH1A1L3MBTL1BACE1POLBKMT2A | |
| SCHEMBL8371348 | 0.70 | DHODH (0.39) | ALDH1A1L3MBTL1POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348342-B2 | Heterocyclic compounds process for their preparation and pharmaceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LIMITED (IN) | 2008-03-25 | — | — | US | disclosed |
| CN-100351237-C | Heterocyclic compounds, process for their preparation, pharmaceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LTD (IN) | 2007-11-28 | — | — | CN | disclosed |
| US-20050277678-A1 | Heterocyclic compounds process for their preparation and pharmceutical compositions containing them and their use in medicine | CADILA HEALTHCARE LIMITED (IN) | 2005-12-15 | — | — | US | disclosed |
| CN-1642918-A | Novel hererocyclic compound and preparation thereof and medicine composition containing same and use thereof in medicine | CADILA HEALTHCARE LTD (IN) | 2005-07-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277678-A1 | Heterocyclic compounds process for their preparation and pharmceutical compositions containing them and their use in medicine | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HPGDS, LTC4S | ALDH1A1 1681/4885L3MBTL1 4884/4885HPGD 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.