Sugi Predict

Sugi Predict / Compounds / SCHEMBL741941

SCHEMBL741941

SCHEMBL741941

Nc1cc(Br)c(F)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ PKM P14618 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ CA1 P00915 2/20 0.36
▸ CA2 P00918 2/20 0.36
▸ CA9 Q16790 2/20 0.36
▸ HSD17B10 Q99714 4/20 0.36
▸ ALOX15 P16050 3/20 0.36
▸ CYP3A4 P08684 2/20 0.36
▸ KDM1A O60341 4/20 0.35
▸ KCNH2 Q12809 2/20 0.35
▸ KDM1B Q8NB78 2/20 0.35
▸ CA12 O43570 1/20 0.34
▸ ADRB2 P07550 1/20 0.33
▸ HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30193870 1.00 ALDH1A1 (0.37) ALDH1A1KDM4EMEN1GAAMAPT
Hydrochloric Acid SCHEMBL16893994 0.98 KDM4E (0.35) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL12056456 0.91 ALDH1A1 (0.37) ALDH1A1KDM4EMEN1GAAMAPT
Hydrochloric Acid SCHEMBL28774061 0.88 ALDH1A1 (0.35) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL4847829 0.81 CA9 (0.38) ALDH1A1KDM4EMAPTL3MBTL1CA1
SCHEMBL1697562 0.79 ALOX15 (0.38) KDM4EMAPTL3MBTL1CA9HSD17B10
SCHEMBL30687171 0.79 ALOX15 (0.38) KDM4EMAPTL3MBTL1CA9HSD17B10
SCHEMBL29902922 0.79 ALDH1A1 (0.42) ALDH1A1MEN1GAAMAPTKMT2A
SCHEMBL932471 0.79 ALDH1A1 (0.42) ALDH1A1KDM4EMEN1GAAMAPT
SCHEMBL241198 0.79 ALDH1A1 (0.42) ALDH1A1MEN1GAAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117732452-A Preparation method of solid phase extraction filler special for organophosphorus insecticide 福建省农业科学院农业质量标准与检测技术研究所 2024-03-22 — — CN claimed
US-12637438-B2 Protoporphyrinogen oxidase inhibitors ENKO CHEM, INC. (US) 2026-05-26 — — US disclosed
EP-4703359-A1 IMIDAZOPYRIDINE OR IMIDAZOPYRAZINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Shanghai Simr Biotechnology Co., Ltd. (CN) 2026-03-04 — — EP disclosed
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES KHORA SPV 1 LLC (US) 2025-10-30 — — US disclosed
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases KHORA SPV 1, LLC (US) 2025-06-17 — — US disclosed
US-20250084044-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS ENKO CHEM, INC. (US) 2025-03-13 — — US disclosed
CN-116096720-B Dihydropyrrolo [2,3-d ] pyridazin-7-one derivatives, preparation method and application thereof 上海和誉生物医药科技有限公司 2025-02-07 — — CN disclosed
CN-115867547-B 1H-pyrazole-4-amide derivative, preparation method and application thereof 上海和誉生物医药科技有限公司 2024-12-20 — — CN disclosed
WO-2024238566-A2 PROCESS FOR MANUFACTURING 6-PERFLUOROPHENYL BENZOXAZINONES ENKO CHEM, INC. (US) 2024-11-21 — — WO disclosed
WO-2024222814-A1 CYP11B2 INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF 长春金赛药业有限责任公司 2024-10-31 — — WO disclosed
EP-2430018-A2 BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYMTHASE INHIBITORS Novartis AG (CH) 2012-03-21 — — EP disclosed
CN-101522689-B Pyridooxazeprilone receptor modulators ORGANON NV 2012-01-11 — — CN disclosed
US-7989442-B2 (cis)-8-fluorodibenzo[b,f]pyrido[1,2-d]oxazepine-1-amine derivatives; contraception, hormone replacement therapy (HRT) or gynaecological disorders, adjuvant therapy in cancer N.V. ORGANON (NL) 2011-08-02 — — US disclosed
WO-2010130773-A2 BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYMTHASE INHIBITORS NOVARTIS AG (CH) 2010-11-18 — — WO disclosed
EP-2066677-B1 PYRIDOOXAZEPINE PROGESTERON RECEPTOR MODULATORS ORGANON NV (NL) 2010-08-18 — — EP disclosed
CN-101522689-A Pyridooxaza  progesterone receptor modulators ORGANON NV (NL) 2009-09-02 — — CN disclosed
EP-2066677-A1 PYRIDOOXAZEPINE PROGESTERON RECEPTOR MODULATORS N.V. Organon (NL) 2009-06-10 — — EP disclosed
CN-101200429-A 2-nitro-4,5-dihalogenated phenol and 2-amino-4,5-dihalogenated phenol as well as its salt and method for synthesizing the same SHANGHAI RUIZHI CHEMICAL STUDY (CN) 2008-06-18 — — CN disclosed
US-20080090804-A1 New progesterone receptor modulators N.V. ORGANON (NL) 2008-04-17 — — US disclosed
WO-2008037746-A1 PYRIDOOXAZEPINE PROGESTERON RECEPTOR MODULATORS N.V. ORGANON (NL) 2008-04-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084044-A1 PROTOPORPHYRINOGEN OXIDASE INHIBITORS PPOX, CYP4X1, PNPO ALDH1A1 1008/4885KDM4E 1878/4885MEN1 4497/4885
US-12331039-B2 Inhibitors of fibroblast growth factor receptor kinases FGFR1, FGFR2, FGFR3 ALDH1A1 2169/4885KDM4E 2742/4885MEN1 2735/4885
US-12637438-B2 Protoporphyrinogen oxidase inhibitors PPOX, CYP4X1, CBR3 ALDH1A1 741/4885KDM4E 1491/4885MEN1 4860/4885
US-20250333399-A1 INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES FGFR1, FGFR2, FGFR3 ALDH1A1 2169/4885KDM4E 2742/4885MEN1 2735/4885
US-20080090804-A1 New progesterone receptor modulators PGR, PGRMC2, PGRMC1 ALDH1A1 1822/4885KDM4E 1309/4885MEN1 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.