Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454993 | 0.94 | PKM (0.52) | PKMALDH1A1HSD11B1PTGS2GAA | |
| SCHEMBL36493 | 0.89 | PKM (0.47) | PKMALDH1A1HSD11B1NFE2L2SMN1; SMN2 | |
| SCHEMBL3143634 | 0.89 | PKM (0.47) | PKMALDH1A1HSD11B1NFE2L2SMN1; SMN2 | |
| SCHEMBL503330 | 0.88 | HSD11B1 (0.42) | PKMALDH1A1HSD11B1FFAR4CA1 | |
| SCHEMBL4858460 | 0.86 | PKM (0.58) | PKMALDH1A1HSD11B1TAS2R14GAA | |
| SCHEMBL8497205 | 0.85 | HSD11B1 (0.47) | PKMALDH1A1HSD11B1SMN1; SMN2RORC | |
| SCHEMBL9135546 | 0.84 | ACHE (0.46) | ALDH1A1HSD11B1EGFRERBB2TAS2R14 | |
| SCHEMBL3130157 | 0.83 | PKM (0.46) | PKMALDH1A1HSD11B1FFAR4NFE2L2 | |
| SCHEMBL503373 | 0.83 | PKM (0.46) | PKMALDH1A1HSD11B1FFAR4NFE2L2 | |
| SCHEMBL2960247 | 0.82 | PKM (0.50) | PKMALDH1A1EGFRERBB2TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323284-B2 | Negative type radiation sensitive resin composition | JSR CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20030022095-A1 | Negative type radiation sensitive resin composition | JSR CORPORATION (JP) | 2003-01-30 | — | — | US | disclosed |