SCHEMBL4848840

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1009963	0.83	TRPV1 (0.62)	TRPV1MEN1MAPTTSHRMAPK1
	SCHEMBL4848378	0.80	TRPV1 (0.67)	TRPV1MEN1MAPTTSHRMAPK1
	SCHEMBL4002053	0.77	TRPV1 (0.70)	TRPV1MEN1MAPTTSHRMAPK1
	SCHEMBL18589867	0.75	ALOX5 (0.53)	TRPV1MEN1MAPTTSHRMAPK1
	SCHEMBL1011712	0.74	TRPV1 (1.00)	TRPV1MEN1MAPTTSHRMAPK1
	SCHEMBL4849792	0.73	RAB9A (0.60)	MEN1MAPTRAB9AKMT2ASMN1; SMN2
	SCHEMBL14545188	0.73	ADRA2A (0.48)	MEN1MAPTTSHRMAPK1RAB9A
	SCHEMBL1013534	0.73	TRPV1 (0.71)	TRPV1MEN1MAPTTSHRMAPK1
	SCHEMBL25755091	0.72	KIF11 (0.50)	XDHSLC22A12RAB9ASMN1; SMN2
	SCHEMBL12954657	0.72	TRPV1 (0.69)	TRPV1MEN1MAPTTSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.