Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865215 | 0.84 | HSD17B10 (0.46) | AKR1C3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL2033555 | 0.81 | AKR1C3 (0.52) | AKR1C3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL27607912 | 0.80 | AKR1C3 (0.59) | AKR1C3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL28136021 | 0.78 | MAPT (0.46) | AKR1C3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL8713885 | 0.76 | ALDH1A1 (0.52) | AKR1C3ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL5056827 | 0.76 | AKR1C3 (0.48) | AKR1C3KDM4EMAPTGAAALDH1A1 | |
| Benzophenone SCHEMBL28222900 | 0.75 | ALDH1A1 (0.52) | MAPTGAAALDH1A1LMNAMEN1 | |
| SCHEMBL11593170 | 0.75 | AKR1C3 (0.62) | AKR1C3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL28397888 | 0.74 | ELANE (0.43) | AKR1C3KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL4849052 | 0.73 | G6PD (0.47) | AKR1C3ALDH1A1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342039-B2 | Substituted indole oximes | WYETH (US) | 2008-03-11 | — | — | US | disclosed |
| US-20050119326-A1 | Substituted aryloximes | WYETH (US) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119326-A1 | Substituted aryloximes | IDO2, TDO2, IDO1 | AKR1C3 757/4885KDM4E 594/4885MAPT 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.