SCHEMBL4849784

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4851226	0.82	HTR5A (0.45)	ADRB1BCL9CTNNB1HTR1AHTR2C
	SCHEMBL27671014	0.81	DRD2 (0.46)	SIGMAR1HTR1AHTR2AHTR2C
	Hydrochloric Acid SCHEMBL4859677	0.80	DRD2 (0.46)	SIGMAR1HTR1AHTR2AHTR2C
	SCHEMBL4852992	0.79	HTR1A (0.51)	HTR3AHTR3EHTR3BHTR3DHTR3C
	SCHEMBL27650931	0.76	HTR3A (0.48)	HTR3AHTR3EHTR3BHTR3DHTR3C
	SCHEMBL4854330	0.73	ALDH1A1 (0.41)	KMT2A
	SCHEMBL2866470	0.73	HTR3A (0.65)	HTR3AHTR3EHTR3BHTR3DHTR3C
	Hydrochloric Acid SCHEMBL2876565	0.72	HTR3A (0.64)	HTR3AHTR3EHTR3BHTR3DHTR3C
	SCHEMBL2874319	0.71	HTR3A (0.77)	HTR3AHTR3EHTR3BHTR3DHTR3C
	SCHEMBL7412675	0.71	HTR3A (0.71)	HTR3AHTR3EHTR3BHTR3DHTR3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.