SCHEMBL4852226

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13988024	0.90	HTR1A (0.43)	DRD3DRD4HTR1AHTR2AHTR7
	SCHEMBL4851846	0.90	DRD3 (0.44)	ACHEDRD3DRD4HTR1AHTR2A
	SCHEMBL4856265	0.89	HTR1A (0.42)	ACHEDRD3DRD4HTR1AHTR2A
	SCHEMBL4861958	0.89	ACHE (0.55)	ACHEALOX15
	SCHEMBL4861872	0.88	MAOA (0.47)	DRD3DRD4HTR1AHTR2AHTR7
	SCHEMBL4854054	0.84	ACHE (0.40)	ACHEDRD4DRD2
	SCHEMBL4851844	0.83	ALDH1A1 (0.47)	ALOX15
	SCHEMBL13987129	0.82	DRD4 (0.42)	ACHEDRD4HTR1ADRD2
	SCHEMBL4860680	0.81	TDP1 (0.45)	ACHE
	SCHEMBL4861851	0.81	ACHE (0.40)	ACHEDRD4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.