Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | METAP2 | P50579 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324689 | 1.00 | HSD17B10 (0.58) | HSD17B10ALDH1A1GAAMETAP2HSP90AA1 | |
| SCHEMBL2056464 | 0.83 | MEN1 (0.49) | HSD17B10ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL12536447 | 0.83 | ALDH1A1 (0.49) | HSD17B10ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL17380970 | 0.83 | TLR8 (0.44) | HSD17B10ALDH1A1GAAHSP90AA1HSP90AB1 | |
| SCHEMBL3362266 | 0.81 | KDM4E (0.60) | HSD17B10ALDH1A1GAAMETAP2HSP90AA1 | |
| SCHEMBL6229280 | 0.81 | ALPL (0.62) | HSD17B10ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL17380968 | 0.81 | NCOA1 (0.45) | HSD17B10GAAKDM4ENPC1NCOA1 | |
| SCHEMBL12536509 | 0.80 | PDE5A (0.45) | HSD17B10ALDH1A1GAAKDM4EHPGD | |
| SCHEMBL14731246 | 0.80 | SCN9A (0.51) | HSD17B10GAAMETAP2KDM4EMAPT | |
| SCHEMBL1856664 | 0.80 | ALDH1A1 (0.57) | HSD17B10ALDH1A1KDM4EHPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250145628-A1 | PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | NOVO NORDISK A/S (DK) | 2025-05-08 | — | — | US | disclosed |
| WO-2025064210-A1 | INHIBITORS OF BILIVERDIN REDUCTASE B (BLVRB) | BLOOD CELL TECHNOLOGIES, LLC (US) | 2025-03-27 | — | — | WO | disclosed |
| EP-4479402-A1 | PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | Novo Nordisk A/S (DK) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023155004-A1 | PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | INVERSAGO PHARMA INC. (CA) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023155004-A1 | PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | INVERSAGO PHARMA INC. (CA) | 2023-08-24 | — | — | WO | disclosed |
| US-9969741-B2 | Pyrazolotriazines as inhibitors of nucleases | MASARYKOVA UNIVERZITA (CZ) | 2018-05-15 | — | — | US | disclosed |
| US-9969741-B2 | Pyrazolotriazines as inhibitors of nucleases | MASARYKOVA UNIVERZITA (CZ) | 2018-05-15 | — | — | US | disclosed |
| EP-2957562-B1 | PYRAZOLOTRIAZINES AS INHIBITORS OF NUCLEASES | UNIV MASARYKOVA (CZ) | 2017-12-20 | — | — | EP | disclosed |
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| US-20130053341-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL COMPANY (JP) | 2013-02-28 | — | — | US | disclosed |
| EP-2415840-A1 | NOVEL AZOMETHINE COMPOUND AND THERMAL TRANSFER SHEET USING THE SAME AZOMETHINE COMPOUND PIGMENT | Dai Nippon Printing Co., Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20110129624-A1 | NOVEL AZOMETHINE COMPOUND AND THERMAL TRANSFER SHEET USING COLORING MATTER OF THE AZOMETHINE COMPOUND | DAI NIPPON PRINTING CO., LTD. (JP) | 2011-06-02 | — | — | US | disclosed |
| US-20110129624-A1 | NOVEL AZOMETHINE COMPOUND AND THERMAL TRANSFER SHEET USING COLORING MATTER OF THE AZOMETHINE COMPOUND | DAI NIPPON PRINTING CO., LTD. (JP) | 2011-06-02 | — | — | US | disclosed |
| US-7393870-B2 | 3-(heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ALLERGAN, INC. (US) | 2008-07-01 | — | — | US | disclosed |
| US-20060074116-A1 | 3-(Heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ALLERGAN, INC. | 2006-04-06 | — | — | US | disclosed |
| US-7005444-B2 | 3-(heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ALLERGAN, INC. (US) | 2006-02-28 | — | — | US | disclosed |
| US-20030130328-A1 | 3-(Heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ALLERGAN, INC. | 2003-07-10 | — | — | US | disclosed |
| US-6559173-B1 | organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation. | ALLERGAN, INC. | 2003-05-06 | — | — | US | disclosed |
| WO-2003026650-A1 | 3-(HETEROARYLAMINO)METHYLENE-1,3-DIHYDRO-2H-INDOL-2-ONES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2003-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129624-A1 | NOVEL AZOMETHINE COMPOUND AND THERMAL TRANSFER SHEET USING COLORING MATTER OF THE AZOMETHINE COMPOUND | INMT, MNS1, IK | HSD17B10 3335/4885ALDH1A1 1335/4885GAA 4760/4885 |
| US-20250145628-A1 | PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | CNR1, CNR2, TRPV1 | HSD17B10 4155/4885ALDH1A1 1990/4885GAA 4654/4885 |
| US-20060074116-A1 | 3-(Heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ERBB2, MKI67, CDK2 | HSD17B10 3354/4885ALDH1A1 2360/4885GAA 2732/4885 |
| US-20130053341-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PPP3CB, PTPRG | HSD17B10 2306/4885ALDH1A1 2732/4885GAA 1062/4885 |
| US-20030130328-A1 | 3-(Heteroarylamino)methylene-1, 3-dihydro-2H-indol-2-ones as kinase inhibitors | ERBB2, MKI67, CDK2 | HSD17B10 3354/4885ALDH1A1 2360/4885GAA 2732/4885 |
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | HSD17B10 2489/4885ALDH1A1 2216/4885GAA 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.