Hexamethylbenzene

Hexamethylbenzene

SCHEMBL4863600

Cc1c(C)c(C)c(C)c(C)c1C.[Ru]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002040494-A1 RUTHENIUM-ARYL-COMPOUNDS IN CANCER THERAPY UNIVERSITY OF YORK (GB) 2002-05-23 WO claimed
EP-2865446-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SECONDARY ALCOHOL KANTO KAGAKU (JP) 2021-09-22 EP disclosed
US-9174906-B2 Process for producing optically active secondary alcohol KANTO KAGAKU KABUSHIKI KAISHA (JP) 2015-11-03 US disclosed
EP-2865446-A1 Process for producing optically active secondary alcohol Kanto Kagaku Kabushiki Kaisha (JP) 2015-04-29 EP disclosed
US-20150031920-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SECONDARY ALCOHOL NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) 2015-01-29 US disclosed
US-8722912-B2 Metal complex compound and process for producing amides utilizing the metal complex compound NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) 2014-05-13 US disclosed
US-20130131366-A1 Metal Complex Compound and Process for Producing Amides Utilizing the Metal Complex Compound NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) 2013-05-23 US disclosed
CN-101646678-B heteroaryl derivatives NIPPON SHINYAKU CO LTD 2012-05-30 CN disclosed
CN-102234294-A Novel process for preparing (C6Me6)2Ru organic metal complex UNIV BEIJING CHEMICAL 2011-11-09 CN disclosed
CN-101646678-A Heteroaryl Derivatives NIPPON SHINYAKU CO LTD JP 2010-02-10 CN disclosed
US-7332622-B2 Process for preparing optically active nitro compounds and cyano compounds KANTO KAGUKU KABUSHIKI KAISHA (JP) 2008-02-19 US disclosed
EP-1439159-B1 Process for producing optically active compound KANTO KAGAKU (JP) 2007-06-20 EP disclosed
EP-1308435-B1 Process for producing optically active amino alcohols KANTO KAGAKU (JP) 2005-12-28 EP disclosed
CN-1626501-A Process for preparing optically active nitro compounds and cyano compounds KANTO KAGAKU (JP) 2005-06-15 CN disclosed
US-20050101787-A1 Process for preparing optically active nitro compounds and cyano compounds KANTO KAGAKU KABUSHIKI KAISHA (JP) 2005-05-12 US disclosed
EP-1512678-A1 Process for preparing optically active nitro compounds and cyano compounds Kanto Kagaku Kabushiki Kaisha (JP) 2005-03-09 EP disclosed
EP-1439159-A1 Process for producing optically active compound Kanto Kagaku Kabushiki Kaisha (JP) 2004-07-21 EP disclosed
EP-1308435-A2 Process for producing optically active amino alcohols Kanto Kagaku Kabushiki Kaisha (JP) 2003-05-07 EP disclosed
WO-2002040494-A1 RUTHENIUM-ARYL-COMPOUNDS IN CANCER THERAPY UNIVERSITY OF YORK (GB) 2002-05-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031920-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SECONDARY ALCOHOL ADH1A, ADH1C, ADH5 RXFP1 2289/4885
US-20130131366-A1 Metal Complex Compound and Process for Producing Amides Utilizing the Metal Complex Compound AP2M1, ASH2L, AP2A1 RXFP1 3213/4885
US-20050101787-A1 Process for preparing optically active nitro compounds and cyano compounds NOS1, NOS2, NOX1 RXFP1 3833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.