Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017806 | 0.84 | SLC6A12 (0.33) | GRM2CYP11B2 | |
| SCHEMBL4859086 | 0.84 | GRM2 (0.36) | GRM2CACNA1GCACNA1HCACNA1IPRMT5 | |
| SCHEMBL4853073 | 0.81 | TUBB4A (0.41) | GRM2 | |
| SCHEMBL17865299 | 0.80 | HPD (0.47) | HPD | |
| SCHEMBL14344337 | 0.76 | HPD (0.44) | HPD | |
| SCHEMBL14344387 | 0.76 | HPD (0.50) | HPD | |
| SCHEMBL14044665 | 0.74 | GRM2 (0.30) | GRM2 | |
| SCHEMBL10080579 | 0.74 | HPD (0.42) | HPD | |
| SCHEMBL115363 | 0.73 | HPD (0.41) | HPD | |
| SCHEMBL17400859 | 0.72 | HPD (0.42) | HPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216975-B2 | Method of labelling soya varieties | Syngenta Crop Protection Inc (US) | 2012-07-10 | — | — | US | disclosed |
| US-8216975-B2 | Method of labelling soya varieties | Syngenta Crop Protection Inc (US) | 2012-07-10 | — | — | US | disclosed |
| US-20100305095-A1 | Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs | SYNGENTA LIMITED (GB) | 2010-12-02 | — | — | US | disclosed |
| US-20100305095-A1 | Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs | SYNGENTA LIMITED (GB) | 2010-12-02 | — | — | US | disclosed |
| US-20090326072-A1 | USE OF 2-(2-NITRO-4-TRIFLUOROMETHYLBENZOYL)-l,3- CYCLOHEXANEDIONE IN THE TREATMENT OF PARKINSON'S DISEASE | SYNGENTA LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-20090326072-A1 | USE OF 2-(2-NITRO-4-TRIFLUOROMETHYLBENZOYL)-l,3- CYCLOHEXANEDIONE IN THE TREATMENT OF PARKINSON'S DISEASE | SYNGENTA LIMITED (GB) | 2009-12-31 | — | — | US | disclosed |
| US-7439207-B2 | 2,6 substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | BAYER CROPSCIENCE AG (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7439207-B2 | 2,6 substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | BAYER CROPSCIENCE AG (DE) | 2008-10-21 | — | — | US | disclosed |
| WO-2008020150-A1 | USE OF HPPD INHIBITORS IN THE TREATMENT OF DEPRESSION AND/OR WITHDRAWAL SYMPTOMS ASSOCIATED WITH ADDICTIVE DRUGS | SYNGENTA LIMITED (GB) | 2008-02-21 | — | — | WO | disclosed |
| US-20050020451-A1 | 2,6 Substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | BAYER CROPSCIENCE AG (DE) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305095-A1 | Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs | HPD, PGD, PEPD | HPD 1/4885GRM2 121/4885TRPV1 3870/4885 |
| US-20050020451-A1 | 2,6 Substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | PDHX, PRDX6, CBR3 | HPD 22/4885GRM2 611/4885TRPV1 4076/4885 |
| US-20090326072-A1 | USE OF 2-(2-NITRO-4-TRIFLUOROMETHYLBENZOYL)-l,3- CYCLOHEXANEDIONE IN THE TREATMENT OF PARKINSON'S DISEASE | SNCA, PARK7, NLN | HPD 204/4885GRM2 410/4885TRPV1 945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.