SCHEMBL115363

SCHEMBL115363

COCCOCc1nc(C(F)(F)F)ccc1C(=O)C1C(=O)CCCC1=O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPD P32754 1/20 0.41
HCRTR1 O43613 1/20 0.33
HCRTR2 O43614 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
PDE11A Q9HCR9 1/20 0.32
HTR1A P08908 1/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
DRD3 P35462 1/20 0.32
HTR2B P41595 1/20 0.32
IDH1 O75874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22443003 0.90 HPD (0.33) HPDHCRTR1HCRTR2NPC1RAB9A
SCHEMBL14189387 0.89 HPD (0.41) HPD
SCHEMBL17400859 0.89 HPD (0.42) HPD
SCHEMBL14344337 0.89 HPD (0.44) HPDHCRTR1
SCHEMBL20760039 0.88 MAPK1 (0.41) HPDHCRTR1HCRTR2NPC1RAB9A
SCHEMBL13383747 0.86 DRD2 (0.31) NPC1RAB9ADRD2DRD4
SCHEMBL19866288 0.86 HCRTR1 (0.32) HCRTR1HCRTR2NPC1RAB9ADRD2
SCHEMBL10080579 0.86 HPD (0.42) HPD
SCHEMBL14465227 0.85 HPD (0.30) HPD
SCHEMBL30177122 0.85 DRD2 (0.32) HCRTR1HCRTR2NPC1RAB9APDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 996 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311588-A1 SYNERGISTIC HERBICIDAL COMBINATIONS COMPRISING TEMBOTRIONE BAYER CROPSCIENCE AG (DE) 2010-12-09 US claimed
US-20100304973-A1 HERBICIDAL COMBINATIONS COMPRISING TEFURYLTRIONE FOR USE IN RICE CROPS BAYER CROPSCIENCE AG (DE) 2010-12-02 US claimed
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides BAYER AKTIENGESELLSCHAFT (DE) 2026-03-03 US disclosed
US-20250359550-A1 METHOD FOR WEED CONTROL IN LAWN OR TURF DISCOVERY PURCHASER CORPORATION (US) 2025-11-27 US disclosed
EP-4651716-A1 SOPHOROLIPIDS AND SOPHOROLIPID DERIVATIVES AS TANK MIX ADDITIVES AND ADJUVANTS IN CROP PROTECTION FORMULATIONS Locus Solutions IPCO, LLC (US) 2025-11-26 EP disclosed
US-12458024-B2 Compound combination with superior herbicidal activity BAYER AKTIENGESELLSCHAFT (DE) 2025-11-04 US disclosed
US-20250275532-A1 LOW DRIFT AQUEOUS LIQUID FORMULATIONS FOR LOW, MEDIUM, AND HIGH SPRAY VOLUME APPLICATION BAYER AKTIENGESELLSCHAFT (DE) 2025-09-04 US disclosed
US-20250261643-A1 METHOD FOR WEED CONTROL IN LAWN OR TURF BAYER CROPSCIENCE LP 2025-08-21 US disclosed
WO-2025078128-A1 PYRIDAZIN-3-ONE-4-YLOXADIAZINES AS NOVEL FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-04-17 WO disclosed
EP-4521922-A1 LOW DRIFT AQUEOUS LIQUID FORMULATIONS FOR LOW, MEDIUM, AND HIGH SPRAY VOLUME APPLICATION Bayer Aktiengesellschaft (DE) 2025-03-19 EP disclosed
WO-2025032038-A1 PYRIDAZIN-4-YLOXADIAZINES AS NOVEL FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-02-13 WO disclosed
US-20090156406-A1 Polymer Composite Film With Biocide Functionality BAYER INNOVATION GMBH (DE) 2009-06-18 US disclosed
US-20090156406-A1 Polymer Composite Film With Biocide Functionality BAYER INNOVATION GMBH (DE) 2009-06-18 US disclosed
US-20090137393-A1 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE BAYER CROPSCIENCE AG (DE) 2009-05-28 US disclosed
WO-2009012887-A1 POLYMER COMPOSITE MATERIAL WITH BIOCIDE FUNCTIONALITY BAYER INNOVATION GMBH (DE) 2009-01-29 WO disclosed
WO-2009007014-A1 WATER-SOLUBLE CONCENTRATES OF 3-(2-ALKOXY-4-CHLORO-6-ALKYLPHENYL)-SUBSTITUTED TETRAMATES AND THEIR CORRESPONDING ENOLS BAYER CROPSCIENCE AG (DE) 2009-01-15 WO disclosed
US-20080305955-A1 Spiroketal-Substituted Cyclic Ketoenols BAYER CROPSCIENCE AG (DE) 2008-12-11 US disclosed
US-20080167188-A1 Herbicide Combinations Comprising Special Ketoenoles BAYER CROPSCIENCE AG (DE) 2008-07-10 US disclosed
US-20080167188-A1 Herbicide Combinations Comprising Special Ketoenoles BAYER CROPSCIENCE AG (DE) 2008-07-10 US disclosed
WO-2007140881-A1 ALKOXYALKYL-SUBSTITUTED CYCLIC KETO-ENOLS BAYER CROPSCIENCE AG (DE) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565489-B2 Heterocyclyl pyrimidines and triazines as novel fungicides CBR1, CBR3, NOX1 HPD 139/4885HCRTR1 103/4885HCRTR2 159/4885
US-20100311588-A1 SYNERGISTIC HERBICIDAL COMBINATIONS COMPRISING TEMBOTRIONE DDT, TUBB, TUBB3 HPD 177/4885HCRTR1 844/4885HCRTR2 892/4885
US-20090156406-A1 Polymer Composite Film With Biocide Functionality PUF60, PARG, PRR12 HPD 615/4885HCRTR1 2491/4885HCRTR2 3711/4885
US-20100304973-A1 HERBICIDAL COMBINATIONS COMPRISING TEFURYLTRIONE FOR USE IN RICE CROPS DDT, DHFR, HACL2 HPD 61/4885HCRTR1 1427/4885HCRTR2 1116/4885
US-20080167188-A1 Herbicide Combinations Comprising Special Ketoenoles DDT, NOTUM, CA3 HPD 16/4885HCRTR1 456/4885HCRTR2 343/4885
US-20250359550-A1 METHOD FOR WEED CONTROL IN LAWN OR TURF NOTUM, WASF2, ASF1A HPD 2805/4885HCRTR1 2892/4885HCRTR2 4547/4885
US-12458024-B2 Compound combination with superior herbicidal activity DDT, AADAC, DPP7 HPD 18/4885HCRTR1 936/4885HCRTR2 1304/4885
US-20090137393-A1 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE DDT, CYP1B1, CNPY2 HPD 45/4885HCRTR1 2548/4885HCRTR2 2378/4885
US-20080305955-A1 Spiroketal-Substituted Cyclic Ketoenols AKR1D1, PDHX, KHK HPD 82/4885HCRTR1 428/4885HCRTR2 687/4885
US-20250261643-A1 METHOD FOR WEED CONTROL IN LAWN OR TURF WASF2, NOTUM, ASF1A HPD 1611/4885HCRTR1 3537/4885HCRTR2 4609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.