SCHEMBL486575

SCHEMBL486575

CS(=O)(=O)c1ccc(NN)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.64
CA1 P00915 3/20 0.64
CA2 P00918 3/20 0.64
CA9 Q16790 2/20 0.64
CA4 P22748 1/20 0.64
CA6 P23280 1/20 0.64
CA5A P35218 1/20 0.64
CA7 P43166 1/20 0.64
CA14 Q9ULX7 1/20 0.64
CA5B Q9Y2D0 1/20 0.64
ALDH1A1 P00352 2/20 0.61
MAPT P10636 2/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
KDM4E B2RXH2 1/20 0.55
LMNA P02545 1/20 0.55
GAA P10253 1/20 0.55
ENPP2 Q13822 2/20 0.50
TGM2 P21980 1/20 0.48
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL839104 0.98 CA12 (0.61) CA12CA1CA2CA9CA4
Hydrochloric Acid SCHEMBL8856800 0.81 CA12 (0.44) CA12CA1CA2CA9CA4
SCHEMBL25667539 0.80 ENPP2 (0.54) CA12CA1CA2CA9MEN1
SCHEMBL4640918 0.80 ALDH1A1 (0.79) CA12CA1CA2CA9CA4
SCHEMBL2376239 0.79 ENPP2 (0.72) ENPP2PTGS2
Hydrochloric Acid SCHEMBL5142727 0.78 ALDH1A1 (0.76) CA12CA1CA2CA9CA4
SCHEMBL1144444 0.78 CA2 (1.00) CA12CA1CA2CA9CA4
SCHEMBL2017578 0.78 CA12 (0.64) CA12CA1CA2CA9ALDH1A1
SCHEMBL5339648 0.77 CA1 (0.59) CA12CA1CA2CA9CA4
SCHEMBL5893440 0.77 CA12 (0.59) CA12CA1CA2CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110714208-B Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-12-29 CN claimed
CN-110714208-A Method for preparing 6- (sulfonyl methyl) phenanthridine compound through electrocatalysis 常州工学院 2020-01-21 CN claimed
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US claimed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP claimed
JP-6234956-A None JP disclosed
EP-4603480-A1 INDOLE PHTHALOCYANINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN TUMOR DIAGNOSIS IMAGING Jiangsu Yahong Meditech Co., Ltd. (CN) 2025-08-20 EP disclosed
EP-4596537-A1 NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF JD Bioscience Inc. (KR) 2025-08-06 EP disclosed
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF EPIVARIO, INC. 2025-06-12 US disclosed
CN-119768391-A Indole phthalocyanine compound, preparation method thereof and application thereof in tumor diagnostic imaging 江苏亚虹医药科技股份有限公司 2025-04-04 CN disclosed
WO-2025022871-A1 ANAEROBIC ADHESIVE, CURED PRODUCT, BONDED STACK, AND MOTOR ソマール株式会社 2025-01-30 WO disclosed
US-12133852-B2 ACSS2 inhibitors and methods of use thereof EPIVARIO, INC. (US) 2024-11-05 US disclosed
WO-2024078579-A1 INDOLE PHTHALOCYANINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN TUMOR DIAGNOSIS IMAGING 江苏亚虹医药科技股份有限公司 2024-04-18 WO disclosed
US-4298676-A PH-SENSITIVE HYDRAZONE COMPOUNDS, ANTIFOGGING AGENTS POLAROID CORPORATION (US) 1981-11-03 US disclosed
US-4269925-A PH-SENSITIVE ANTIFOGGING AGENTS HAVING AN ADDITION POLYMER BACKBONE WITH PENDANT ELECTRONEGATIVELY-SUBSTITUTED HYDROCARBYL HYDRAZINE GROUPS; PHOTO SELF-DEVELOPMENT FILMS POLAROID CORPORATION (US) 1981-05-26 US disclosed
US-4268592-A PYRAZOLONE MAGENTA COUPLER CIBA-GEIGY AG (CH) 1981-05-19 US disclosed
US-4257952-A PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES STERLING DRUG INC. (US) 1981-03-24 US disclosed
US-4172834-A ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS STERLING DRUG INC. (US) 1979-10-30 US disclosed
US-4151210-A Process for the production of phenylalkyl sulphones CIBA-GEIGY CORPORATION (US) 1979-04-24 US disclosed
US-4062864-A ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1977-12-13 US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186433-A1 ACSS2 INHIBITORS AND METHODS OF USE THEREOF ACSS2, GLS2, ADSS2 CA12 466/4885CA1 634/4885CA2 1483/4885
US-12133852-B2 ACSS2 inhibitors and methods of use thereof ACSS2, GLS2, ADSS2 CA12 466/4885CA1 634/4885CA2 1483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.