SCHEMBL486654

SCHEMBL486654

CCCCCCOc1ccc(NC(=O)CN(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
FAAH O00519 13/20 0.58
S1PR1 P21453 3/20 0.58
S1PR3 Q99500 3/20 0.58
ALDH1A1 P00352 1/20 0.53
TP53 P04637 1/20 0.52
TSHR P16473 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486730 0.82 THRB (0.60) FAAHTSHR
SCHEMBL4423437 0.82 GAA (0.70) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL25885457 0.81 GAA (0.77) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL5223000 0.81 FAAH (0.70) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL5221933 0.81 FAAH (0.70) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL5215792 0.81 FAAH (0.70) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL5221042 0.81 FAAH (0.70) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL5218334 0.81 FAAH (0.70) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL2089631 0.81 FAAH (0.70) GAAL3MBTL1FAAHS1PR1S1PR3
SCHEMBL2097878 0.79 GAA (0.69) GAAL3MBTL1FAAHS1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
CN-104666246-A Orally Bioavailable Lipid-based Constructs SDG INC AN OHIO CORPRATION 2015-06-03 CN claimed
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal SDG, INC. (US) 2011-06-09 US claimed
WO-2011022396-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2011-02-24 WO claimed
US-7871641-B2 Hepatocyte-targeting vehicle for delivery of glargine insulin to a mammal SDG, INC. (US) 2011-01-18 US claimed
US-7858116-B2 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. (US) 2010-12-28 US claimed
CN-101917971-A Orally bioavailable lipid-based structures SDG INC AN OHIO CORP 2010-12-15 CN claimed
EP-2205217-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS SDG, INC. (an Ohio Corporation ) (US) 2010-07-14 EP claimed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US claimed
CN-101237854-A Lipid construct for delivery of insulin to a mammal SDG INC (US) 2008-08-06 CN claimed
EP-1883394-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, Inc. (US) 2008-02-06 EP claimed
WO-2006127361-A2 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG, INC. (US) 2006-11-30 WO claimed
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal SDG, INC. 2006-10-05 US claimed
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal SDG, INC. 2006-10-05 US claimed
EP-1005327-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 2000-06-07 EP claimed
EP-0999855-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, Inc. (US) 2000-05-17 EP claimed
US-6063400-A CARRIER; DIAGNOSTIC OR THERAPEUTIC AGENT AND SEQUESTERING AGENT SDG, INC. (US) 2000-05-16 US claimed
WO-1999004824-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, INC. (US) 1999-02-04 WO claimed
WO-1999001110-A1 TARGETED LIPOSOMAL CONSTRUCTS FOR DIAGNOSTIC AND THERAPEUTIC USES SDG, INC. (US) 1999-01-14 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 GAA 2501/4885L3MBTL1 3625/4885FAAH 844/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 GAA 3404/4885L3MBTL1 3724/4885FAAH 1870/4885
US-20060222698-A1 Hepatocyte delivery vehicle for delivery of glargine insulin to a mammal INSR, GPR119, GCG GAA 193/4885L3MBTL1 4498/4885FAAH 3321/4885
US-20090087479-A1 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 GAA 2586/4885L3MBTL1 2707/4885FAAH 1125/4885
US-20110135725-A1 Lipid Construct for Delivery of Insulin to a Mammal INSR, IAPP, GPR119 GAA 1226/4885L3MBTL1 3266/4885FAAH 461/4885
US-20060222697-A1 Hepatocyte delivery vehicle for delivery of a combination of recombinant human regular insulin and recombinant human insulin isophane to a mammal INSR, INSRR, IAPP GAA 3529/4885L3MBTL1 4067/4885FAAH 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.