Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4865612 | 0.90 | CTSV (0.41) | ALDH1A1SMN1; SMN2MAPTCYP2C19KDM4E | |
| SCHEMBL6041580 | 0.81 | REN (0.45) | ALDH1A1HTTSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL4874160 | 0.80 | ADORA2B (0.39) | MEN1KMT2APOLBCTSVCTSL | |
| SCHEMBL4873106 | 0.79 | ALOX5 (0.33) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4874370 | 0.78 | JAK2 (0.46) | SMN1; SMN2GAAKDM4E | |
| SCHEMBL4867749 | 0.78 | ADORA2B (0.33) | MAPTCYP1A2CYP2C9CYP2C19MAPK1 | |
| SCHEMBL6041324 | 0.78 | REN (0.59) | REN | |
| SCHEMBL14256311 | 0.77 | TACR1 (0.41) | ALDH1A1MAPTKDM4ERAB9AREN | |
| SCHEMBL4874927 | 0.77 | USP30 (0.46) | — | |
| SCHEMBL4865775 | 0.77 | GPR119 (0.40) | KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338965-B2 | 3,4-disubstituted, 3,5-disubstituted and 3,4,5-substituted piperidines | PHARMACIA & UPJOHN COMPANY (US) | 2008-03-04 | — | — | US | disclosed |