Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872665 | 0.87 | — | — | |
| SCHEMBL4872659 | 0.78 | HSD17B10 (0.37) | HSD17B10 | |
| SCHEMBL3510332 | 0.70 | RECQL (0.40) | TSHRALDH1A1RECQL | |
| SCHEMBL4872675 | 0.68 | — | — | |
| SCHEMBL3514480 | 0.68 | KMT2A (0.37) | KDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL3516033 | 0.66 | ALDH1A1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL27615261 | 0.64 | SMN1; SMN2 (0.42) | KDM4ETSHRHSD17B10ALDH1A1 | |
| SCHEMBL4871262 | 0.64 | MEN1 (0.39) | KDM4ETSHRHSD17B10ALDH1A1RECQL | |
| SCHEMBL4871261 | 0.62 | SMN1; SMN2 (0.37) | KDM4ETSHRHSD17B10ALDH1A1RECQL | |
| SCHEMBL12286073 | 0.62 | ALOX5 (0.51) | KDM4EALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402576-B2 | Phosphinic acid analogs of glutamate | GIVAUDAN SA (CH) | 2008-07-22 | — | — | US | disclosed |
| EP-1599487-B1 | PHOSPHINIC ACID ANALOGS OF GLUTAMATE | GIVAUDAN SA (CH) | 2007-07-11 | — | — | EP | disclosed |
| US-20060052616-A1 | Phosphinic acid analogs of glutamate | GIVAUDAN SA (CH) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052616-A1 | Phosphinic acid analogs of glutamate | GLUL, GRIA1, GRM1 | KDM4E 2308/4885TSHR 2006/4885HSD17B10 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.