SCHEMBL487472

SCHEMBL487472

Nc1cccc(S(=O)(=O)c2ccccc2)c1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.87
CA2 P00918 3/20 0.63
CA12 O43570 2/20 0.63
CA1 P00915 2/20 0.63
CA4 P22748 2/20 0.63
CA9 Q16790 2/20 0.63
CA14 Q9ULX7 1/20 0.63
HTR6 P50406 7/20 0.61
TSHR P16473 3/20 0.61
ALDH1A1 P00352 3/20 0.61
HSD17B10 Q99714 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
POLB P06746 1/20 0.59
F2 P00734 1/20 0.52
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
PRMT1 Q99873 1/20 0.51
ANXA2 P07355 1/20 0.50
S100A10 P60903 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27752989 0.96 LMNA (0.95) LMNACA2CA12CA1CA4
SCHEMBL1100221 0.93 LMNA (0.91) LMNACA2CA12CA1CA4
SCHEMBL29635012 0.93 LMNA (1.00) LMNACA2CA12CA1CA4
SCHEMBL5561963 0.93 LMNA (1.00) LMNACA2CA12CA1CA4
SCHEMBL34546 0.93 LMNA (1.00) LMNACA2CA12CA1CA4
SCHEMBL30544199 0.93 LMNA (1.00) LMNACA2CA12CA1CA4
SCHEMBL324628 0.91 LMNA (0.95) LMNACA2CA12CA1CA4
SCHEMBL29692583 0.89 LMNA (0.83) LMNACA2CA12CA1CA4
SCHEMBL8721954 0.89 LMNA (0.83) LMNACA2CA12CA1CA4
SCHEMBL34500 0.89 LMNA (0.83) LMNACA2CA12CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1451160-B1 PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN ICAGEN INC (US) 2010-01-13 EP claimed
US-5260388-A Reacting aromatic diamine with tetracarboxylic anhydride in presence of aromatic dicarboxylic anhydride or monoamine, imidizing; low dielectric characteristics; electronics MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-11-09 US claimed
CN-119432114-A Azo disperse dye and preparation method thereof 蓬莱嘉信染料化工股份有限公司 2025-02-14 CN disclosed
CN-110964342-B Disperse dye composition, disperse dye, and preparation method and application thereof 浙江闰土股份有限公司 2022-08-05 CN disclosed
EP-3842500-A1 POLYIMIDE VARNISH COMPRISING AROMATIC CARBOXYLIC ACID FOR CONDUCTOR COATING AND MANUFACTURING METHOD THEREFOR PI Advanced Materials Co., Ltd. (KR) 2021-06-30 EP disclosed
WO-2020204513-A1 SUBSTRATE FOR HEAT-RESISTANT ELECTRONIC DEVICE 주식회사 엘지화학 2020-10-08 WO disclosed
US-10759765-B2 Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute CE PHARM CO., LTD. (CN) 2020-09-01 US disclosed
US-10556979-B2 Modified polyimide and curable resin composition LG CHEM, LTD. (KR) 2020-02-11 US disclosed
US-20190309118-A1 MODIFIED POLYIMIDE AND CURABLE RESIN COMPOSITION LG CHEM, LTD. (KR) 2019-10-10 US disclosed
US-10316128-B2 Modified polyimide and curable resin composition LG CHEM, LTD. (KR) 2019-06-11 US disclosed
US-20190127337-A1 HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE CE PHARM CO., LTD. (CN) 2019-05-02 US disclosed
EP-0430430-A2 Polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-06-05 EP disclosed
US-5013817-A Monoamine reactant, melt processability MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP disclosed
EP-0081900-B1 ANISOTROPIC POLYMERS HAVING IMPROVED RETENTION OF PHYSICAL PROPERTIES AT ELEVATED TEMPERATURES AND METHODS OF MANUFACTURE THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-05-13 EP disclosed
US-4499256-A Anisotropic polyesteramide polymers having improved retention of physical properties at elevated temperatures and methods of manufacture thereof IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-02-12 US disclosed
EP-0109624-A2 Process for producing shaped articles made from polyurethane-polyurea which may be cellular BASF Aktiengesellschaft (DE) 1984-05-30 EP disclosed
US-4313872-A MONDAZO AND DISAZO DYES CASSELLA AKTIENGESELLSCHAFT (DE) 1982-02-02 US disclosed
US-4082793-A AROMATIC PHOSPHINIC ACIDS CONTAINING SULFONE LINKAGE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-04-04 US disclosed
US-3980677-A Anthraquinone dyestuffs containing sulphonic acid groups BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190127337-A1 HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE AOC1, AOC2, AOC3 LMNA 4664/4885CA2 743/4885CA12 470/4885
US-10759765-B2 Heterocyclic carboxylic acid amide ligand and applications thereof in copper catalyzed coupling reaction of aryl halogeno substitute AOC1, AOC2, AOC3 LMNA 4664/4885CA2 743/4885CA12 470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.