SCHEMBL4877801

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6212186	0.88	BAZ2B (0.57)	MAOAMAOBTP53MAPTNPC1
	SCHEMBL9447608	0.84	NPC1 (0.65)	MAOAMAOBTP53MAPTNPC1
	SCHEMBL20809837	0.83	TP53 (0.56)	MAOAMAOBTP53MAPTNPC1
	SCHEMBL6211660	0.80	ALDH1A1 (0.61)	MAOAMAOBTP53MAPTNPC1
	SCHEMBL6191868	0.79	NPC1 (0.57)	MAOAMAOBTP53MAPTNPC1
	SCHEMBL17813395	0.77	NPC1 (0.52)	MAOAMAOBTP53MAPTNPC1
	SCHEMBL17797704	0.77	NPC1 (0.52)	MAOAMAOBTP53MAPTNPC1
	SCHEMBL8338982	0.77	SLC1A3 (0.61)	MAOATP53MAPTNPC1ALDH1A1
	SCHEMBL15158561	0.77	MAOA (0.61)	MAOAMAOBMAPTNPC1ALDH1A1
	SCHEMBL6190803	0.77	RAB9A (0.56)	MAOAMAOBTP53MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.