Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.32 |
| ▸ | MME | P08473 | 5/20 | 0.32 |
| ▸ | ACE | P12821 | 5/20 | 0.32 |
| ▸ | CPA1 | P15085 | 4/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876772 | 0.90 | ANPEP (0.35) | KDM1AMMP9MMP8MMP14 | |
| SCHEMBL404156 | 0.75 | MMP1 (0.38) | MMP9 | |
| SCHEMBL4876239 | 0.75 | ANPEP (0.36) | MMP8 | |
| SCHEMBL4877868 | 0.74 | CYP3A4 (0.35) | MAPTMAPK1TACR3POLB | |
| SCHEMBL2157188 | 0.74 | CYP3A4 (0.36) | KDM1AMAPTHTT | |
| SCHEMBL4868337 | 0.69 | ANPEP (0.35) | — | |
| SCHEMBL403859 | 0.69 | CSK (0.34) | MMP8 | |
| SCHEMBL5650448 | 0.68 | SMN1; SMN2 (0.42) | NPC1RAB9A | |
| SCHEMBL4878757 | 0.68 | ITGB1 (0.36) | ITGB1ITGA4MMEACECPA1 | |
| SCHEMBL403197 | 0.68 | SIGMAR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | KDM1A 4512/4885ITGB1 2538/4885ITGA4 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.