Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.36 |
| ▸ | MME | P08473 | 7/20 | 0.34 |
| ▸ | ACE | P12821 | 7/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.34 |
| ▸ | CPA1 | P15085 | 5/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876777 | 0.91 | ANPEP (0.37) | — | |
| SCHEMBL4876249 | 0.78 | ANPEP (0.39) | — | |
| SCHEMBL4877871 | 0.77 | PYGL (0.34) | LMNA | |
| SCHEMBL2157193 | 0.77 | SMN1; SMN2 (0.33) | LMNA | |
| SCHEMBL404157 | 0.76 | MMP1 (0.36) | MMEACEACE2CPA1 | |
| SCHEMBL27805645 | 0.72 | KDM4E (0.30) | MME | |
| SCHEMBL403860 | 0.72 | ANPEP (0.35) | — | |
| SCHEMBL27734190 | 0.71 | MMP9 (0.37) | — | |
| SCHEMBL403198 | 0.71 | CHEK1 (0.32) | — | |
| SCHEMBL4868358 | 0.71 | ANPEP (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358359-B2 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060154988-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2006-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154988-A1 | Antibacterial agents | MRPL21, SI, PGLS | ITGB1 2538/4885ITGA4 3436/4885MME 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.