SCHEMBL4879110

SCHEMBL4879110

O=C(O)c1ccccc1C(=O)Oc1ncc[nH]1.[Ni]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
ALOX15 P16050 2/20 0.42
KMT2A Q03164 2/20 0.40
CSNK1A1 P48729 1/20 0.40
TYRO3 Q06418 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
KDM4E B2RXH2 7/20 0.40
HSD17B10 Q99714 2/20 0.40
HPGD P15428 1/20 0.40
LMNA P02545 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
MEN1 O00255 1/20 0.38
NAPRT Q6XQN6 3/20 0.38
MAPT P10636 2/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL11231296 0.91 CSNK1A1 (0.44) ALDH1A1ALOX15KMT2ACSNK1A1TYRO3
SCHEMBL24485 0.83 HPGD (0.51) ALDH1A1ALOX15KMT2ACSNK1A1TYRO3
SCHEMBL10438254 0.82 NPC1 (0.45) KMT2ACSNK1A1TYRO3DYRK1BLMNA
SCHEMBL11111898 0.81 TSHR (0.58) ALDH1A1ALOX15KMT2AHSD17B10CYP1A2
SCHEMBL5323575 0.81 LMNA (0.45) ALDH1A1KMT2AKDM4EHSD17B10LMNA
Biphenyl SCHEMBL7414261 0.76 KMT2A (0.51) ALDH1A1KMT2AKDM4ELMNATDP1
SCHEMBL28455316 0.74 ALDH1A1 (0.52) ALDH1A1ALOX15KMT2AKDM4EHSD17B10
SCHEMBL15234294 0.73 KDM4E (0.41) ALDH1A1ALOX15KMT2AKDM4EHSD17B10
SCHEMBL9063985 0.73 ALDH1A1 (0.40) ALDH1A1KMT2ACSNK1A1TYRO3DYRK1B
SCHEMBL667770 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656979-B1 For sealing a joint, a step, a bond portion, a seam portion, a crack portion or other portions of vehicles 3M INNOVATIVE PROPERTIES COMPANY 2003-12-02 US claimed
US-4948449-A COATING SUBSTRATE WITH STORAGE MIXTURE CONTAINING POLYOL CURING AGENT AND IMIDAZOLE CATALYST MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-08-14 US claimed
US-4772645-A CURABLE, STORAGE STABLE MIXTURES; IMIDAZOLE COMPOUNDS AS CATALYST, POLYOL CURING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-09-20 US claimed
US-20080280127-A1 Heat-Curable Molding Material Pellet Having Multilayer Structure 3M INNOVATIVE PROPERTIES COMPANY 2008-11-13 US disclosed
EP-1718447-A1 HEAT-CURABLE MOLDING MATERIAL PELLET HAVING MULTILAYER STRUCTURE 3M Innovative Properties Company (US) 2006-11-08 EP disclosed
WO-2005087472-A1 HEAT-CURABLE MOLDING MATERIAL PELLET HAVING MULTILAYER STRUCTURE 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-09-22 WO disclosed
EP-1022320-B9 Thermosettable pressure sensitive adhesive sheet MINNESOTA MINING & MFG (US) 2005-06-15 EP disclosed
US-20050051381-A1 Underbody sound damping structure for motor vehicles 3M INNOVATIVE PROPERTIES COMPANY 2005-03-10 US disclosed
EP-1022320-B1 Thermosettable pressure sensitive adhesive sheet MINNESOTA MINING & MFG (US) 2004-12-22 EP disclosed
EP-1187888-B1 BONDED STRUCTURE 3M INNOVATIVE PROPERTIES CO (US) 2004-11-10 EP disclosed
EP-1453670-A1 UNDERBODY SOUND DAMPING STRUCTURE FOR MOTOR VEHICLES 3M Innovative Properties Company (US) 2004-09-08 EP disclosed
WO-1995020635-A2 NOVEL SHEET MATERIAL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-03 WO disclosed
WO-1995013327-A1 TOPOGRAPHICAL METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-18 WO disclosed
WO-1995012647-A1 ANTICORROSION ADHESIVE COMPOSITION AND METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-11 WO disclosed
EP-0639212-A1 TOPOGRAPHICAL METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-02-22 EP disclosed
WO-1994021741-A1 TOPOGRAPHICAL SHEET MATERIAL AND METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-09-29 WO disclosed
WO-1993023487-A2 TOPOGRAPHICAL METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-11-25 WO disclosed
US-4948449-A COATING SUBSTRATE WITH STORAGE MIXTURE CONTAINING POLYOL CURING AGENT AND IMIDAZOLE CATALYST MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-08-14 US disclosed
US-4772645-A CURABLE, STORAGE STABLE MIXTURES; IMIDAZOLE COMPOUNDS AS CATALYST, POLYOL CURING AGENTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-09-20 US disclosed
EP-0245018-A2 Epoxy resin composition MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-11 EP disclosed