Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | CASP1 | P29466 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1809702 | 1.00 | ALOX15 (0.74) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL14140425 | 0.87 | ALOX15 (0.54) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL13600370 | 0.87 | RAB9A (0.67) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL75219 | 0.86 | ALOX15 (1.00) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL10726923 | 0.86 | ALOX15 (1.00) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL12573259 | 0.86 | HSD17B1 (0.57) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL12573258 | 0.86 | APP (0.64) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL620114 | 0.84 | ALOX15 (0.51) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL1267325 | 0.84 | ALOX15 (0.96) | ALOX15TSHRCASP1RAB9AKMT2A | |
| SCHEMBL2684521 | 0.84 | ALOX15 (0.96) | ALOX15TSHRCASP1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | claimed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | claimed |
| US-9034655-B2 | Highly water-soluble, cationic luminescent labels | SETA BIOMEDICALS, LLC (US) | 2015-05-19 | — | — | US | disclosed |
| US-9034655-B2 | Highly water-soluble, cationic luminescent labels | SETA BIOMEDICALS, LLC (US) | 2015-05-19 | — | — | US | disclosed |
| US-20110143387-A1 | HIGHLY WATER-SOLUBLE, CATIONIC LUMINESCENT LABELS | SETA BIOMEDICALS, LLC | 2011-06-16 | — | — | US | disclosed |
| US-20110143387-A1 | HIGHLY WATER-SOLUBLE, CATIONIC LUMINESCENT LABELS | SETA BIOMEDICALS, LLC | 2011-06-16 | — | — | US | disclosed |
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007149395-A2 | 2,5-SUBSTITUTED OXAZOLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER | AMPHORA DISCOVERY CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
| US-4431722-A | POLYCYCLIC QUINONE PIGMENT DISPERSED IN A RESIN BINDER AS CHARGE GENERATING LAYER; ANTIFOGGING AGENTS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015193-A1 | Certain azoles exhibiting ATP-utilizing enzyme inhibitory activity, compositions, and uses thereof | ATP5ME, ATP5MG, ATP5MK | ALOX15 2152/4885TSHR 4714/4885CASP1 3523/4885 |
| US-20110143387-A1 | HIGHLY WATER-SOLUBLE, CATIONIC LUMINESCENT LABELS | SLC7A5, ABCG2, SLC43A1 | ALOX15 4710/4885TSHR 3444/4885CASP1 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.