Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.53 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.51 |
| ▸ | KRAS | P01116 | 1/20 | 0.47 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889967 | 0.89 | MAPKAPK2 (0.55) | SLC6A12SLC6A13MAPKAPK2KRASSOS1 | |
| SCHEMBL4890287 | 0.87 | SOS1 (0.52) | SLC6A12MAPKAPK2KRASSOS1ADRA2A | |
| SCHEMBL4879370 | 0.86 | MAPKAPK2 (0.52) | MAPKAPK2KRASSOS1ADRA2AADRA2B | |
| SCHEMBL4890665 | 0.86 | SOS1 (0.50) | MAPKAPK2KRASSOS1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL4895600 | 0.85 | MAPKAPK2 (0.51) | MAPKAPK2KRASSOS1ADRA2AADRA2B | |
| SCHEMBL4886641 | 0.73 | MAPKAPK2 (0.52) | SLC6A12SLC6A13MAPKAPK2MCHR1 | |
| SCHEMBL4892360 | 0.73 | MAPKAPK2 (0.64) | SLC6A12SLC6A13MAPKAPK2SIGMAR1MCHR1 | |
| SCHEMBL4892984 | 0.72 | MAPKAPK2 (0.63) | SLC6A12SLC6A13MAPKAPK2SIGMAR1MCHR1 | |
| SCHEMBL4894204 | 0.71 | MAPKAPK2 (0.62) | SLC6A12SLC6A13MAPKAPK2SIGMAR1MCHR1 | |
| SCHEMBL4881110 | 0.71 | MAPKAPK2 (0.62) | SLC6A12SLC6A13MAPKAPK2SIGMAR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | claimed |
| EP-1761526-A2 | THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2007-03-14 | — | — | EP | claimed |
| WO-2005118579-A2 | THIAZOLE DERIVATIVES AS CHEMOKINE RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2005-12-15 | — | — | WO | claimed |
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
| US-20080039499-A1 | Chemical Compounds | BOWER JUSTIN F | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039499-A1 | Chemical Compounds | CCR1, CCL11, CXCR1 | SLC6A12 2262/4885SLC6A13 2339/4885NPC1 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.