SCHEMBL4890665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4890287	0.89	SOS1 (0.52)	SOS1KRASADRA2AADRA2BADRA2C
	SCHEMBL4889967	0.88	MAPKAPK2 (0.55)	SOS1KRASADRA2AADRA2BADRA2C
	SCHEMBL4893059	0.86	SLC6A12 (0.53)	SOS1KRASADRA2AADRA2BADRA2C
	SCHEMBL4879370	0.85	MAPKAPK2 (0.52)	SOS1KRASADRA2AADRA2BADRA2C
	Hydrochloric Acid SCHEMBL4895600	0.84	MAPKAPK2 (0.51)	SOS1KRASADRA2AADRA2BADRA2C
	SCHEMBL4885734	0.73	MAPKAPK2 (0.62)	MAPKAPK2SIGMAR1CYP2D6DRD4
	SCHEMBL11311140	0.72	SOS1 (0.73)	SOS1KRASADRA2AADRA2BADRA2C
	SCHEMBL4889803	0.72	PRKAA2 (0.59)	MAPKAPK2SIGMAR1CYP2D6DRD2DRD4
	SCHEMBL4886641	0.71	MAPKAPK2 (0.52)	MAPKAPK2DRD4
	SCHEMBL4889804	0.71	MAPKAPK2 (0.60)	MAPKAPK2SIGMAR1DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.