SCHEMBL4889967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4890287	0.90	SOS1 (0.52)	MAPKAPK2SLC6A12KRASSOS1ADRA2A
	SCHEMBL4893059	0.89	SLC6A12 (0.53)	MAPKAPK2SLC6A12SLC6A13KRASSOS1
	SCHEMBL4879370	0.89	MAPKAPK2 (0.52)	MAPKAPK2KRASSOS1ADRA2AADRA2B
	SCHEMBL4890665	0.88	SOS1 (0.50)	MAPKAPK2DRD4KRASSOS1ADRA2A
	Hydrochloric Acid SCHEMBL4895600	0.88	MAPKAPK2 (0.51)	MAPKAPK2KRASSOS1ADRA2AADRA2B
	SCHEMBL4886641	0.76	MAPKAPK2 (0.52)	MAPKAPK2DRD4SLC6A12SLC6A13
	SCHEMBL4892360	0.75	MAPKAPK2 (0.64)	MAPKAPK2DRD4SLC6A12SLC6A13
	SCHEMBL4892984	0.74	MAPKAPK2 (0.63)	MAPKAPK2DRD4SLC6A12SLC6A13
	SCHEMBL4894204	0.73	MAPKAPK2 (0.62)	MAPKAPK2DRD4SLC6A12SLC6A13
	SCHEMBL4881110	0.73	MAPKAPK2 (0.62)	MAPKAPK2DRD4SLC6A12SLC6A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.