SCHEMBL4880925

SCHEMBL4880925

CC(C)(C)[Si](C)(C)OCCN(C#N)c1ccc(N(C(=O)c2nc[nH]c2C(N)=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.33
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 3/20 0.32
KMT2A Q03164 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
DGAT1 O75907 2/20 0.32
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4878075 0.92 DGAT1 (0.31) DGAT1
SCHEMBL4882264 0.83 MAPT (0.39) MAPTALDH1A1L3MBTL1MAPK1ATM
SCHEMBL4881627 0.76 MAPT (0.35) MAPTALDH1A1MAPK1ATMKDM4E
SCHEMBL4881646 0.74 DGAT1 (0.33) ALDH1A1L3MBTL1DGAT1
SCHEMBL4879118 0.73 DGAT1 (0.33) DGAT1
SCHEMBL4880920 0.71 SCN9A (0.38) MAPTALDH1A1L3MBTL1MAPK1ATM
SCHEMBL4878069 0.69 SMN1; SMN2 (0.35) MAPTALDH1A1MAPK1KDM4EKMT2A
SCHEMBL4881051 0.68 RAB9A (0.38) MAPTALDH1A1L3MBTL1MAPK1KDM4E
SCHEMBL4878149 0.68 LMNA (0.41) MAPTALDH1A1NPSR1
SCHEMBL3614731 0.68 RAB9A (0.39) MAPTALDH1A1L3MBTL1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080214533-A1 Cyclic Iminocarbamates And Their Use BAYER HEALTHCARE AG (DE) 2008-09-04 US disclosed
EP-1819701-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF Bayer HealthCare AG (DE) 2007-08-22 EP disclosed
WO-2006058630-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF BAYER HEALTHCARE AG (DE) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214533-A1 Cyclic Iminocarbamates And Their Use F2, UQCRB, F12 MAPT 4803/4885ALDH1A1 348/4885L3MBTL1 2946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.