Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881351 | 1.00 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2TRPM8MAPT | |
| SCHEMBL4885125 | 0.91 | TRPM8 (0.62) | RAB9ANPC1SMN1; SMN2TRPM8MAPT | |
| SCHEMBL4885116 | 0.91 | TRPM8 (0.62) | RAB9ANPC1SMN1; SMN2TRPM8MAPT | |
| SCHEMBL14148789 | 0.83 | L3MBTL1 (0.57) | SMN1; SMN2TRPM8MAPTTP53HTR2A | |
| SCHEMBL14148791 | 0.81 | L3MBTL1 (0.61) | RAB9ANPC1SMN1; SMN2TRPM8MAPT | |
| SCHEMBL29407319 | 0.81 | L3MBTL1 (0.61) | RAB9ANPC1SMN1; SMN2TRPM8MAPT | |
| SCHEMBL29786680 | 0.80 | LTB4R (0.61) | NPC1TRPM8HDAC3HDAC4HDAC1 | |
| SCHEMBL15219985 | 0.78 | CYP3A4 (0.56) | RAB9ASMN1; SMN2TRPM8LMNAHDAC3 | |
| SCHEMBL22423034 | 0.77 | MAOB (0.67) | RAB9ANPC1SMN1; SMN2MAPTHPGD | |
| Zanthomamide SCHEMBL29407211 | 0.77 | MAPT (0.87) | RAB9ANPC1SMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9894921-B2 | Use of cinnamic acid derivatives containing nitrogen as flavouring agents | SYMRISE AG (DE) | 2018-02-20 | — | — | US | disclosed |
| US-9894921-B2 | Use of cinnamic acid derivatives containing nitrogen as flavouring agents | SYMRISE AG (DE) | 2018-02-20 | — | — | US | disclosed |
| EP-2737807-B1 | Use of nitrogen-containing derivatives of cinnamic acid as flavourants | SYMRISE AG (DE) | 2017-04-05 | — | — | EP | disclosed |
| US-20150272185-A1 | USE OF CINNAMIC ACID DERIVATIVES CONTAINING NITROGEN AS FLAVOURING AGENTS | SYMRISE AG (DE) | 2015-10-01 | — | — | US | disclosed |
| US-20150272185-A1 | USE OF CINNAMIC ACID DERIVATIVES CONTAINING NITROGEN AS FLAVOURING AGENTS | SYMRISE AG (DE) | 2015-10-01 | — | — | US | disclosed |
| US-9144248-B2 | Cinnamamides as savory flavorings | SYMRISE AG (DE) | 2015-09-29 | — | — | US | disclosed |
| US-9144248-B2 | Cinnamamides as savory flavorings | SYMRISE AG (DE) | 2015-09-29 | — | — | US | disclosed |
| EP-2737807-A1 | Use of nitrogen-containing derivatives of cinnamic acid as flavourants | Symrise AG (DE) | 2014-06-04 | — | — | EP | disclosed |
| EP-2529632-B1 | Cinnamic acid amides as spicy flavour agents | SYMRISE AG (DE) | 2013-08-28 | — | — | EP | disclosed |
| US-20120308703-A1 | Cinnamamides as savory flavorings | SYMRISE AG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120308703-A1 | Cinnamamides as savory flavorings | SYMRISE AG (DE) | 2012-12-06 | — | — | US | disclosed |
| EP-2529632-A1 | Cinnamic acid amides as spicy flavour agents | Symrise AG (DE) | 2012-12-05 | — | — | EP | disclosed |
| US-20080038386-A1 | Use of a liquid cooling sensate to provide a pungent, warming or tingling sensate composition | MOZA ASHOK K | 2008-02-14 | — | — | US | disclosed |