Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881965 | 1.00 | NPC1 (0.57) | NPC1RAB9ANLRP3SMN1; SMN2KMT2A | |
| SCHEMBL4887230 | 0.95 | NPC1 (0.57) | NPC1RAB9ANLRP3SMN1; SMN2KMT2A | |
| SCHEMBL4887228 | 0.95 | NPC1 (0.57) | NPC1RAB9ANLRP3SMN1; SMN2KMT2A | |
| SCHEMBL4882773 | 0.88 | LMNA (0.52) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL4882768 | 0.88 | LMNA (0.52) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL4928558 | 0.87 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL4882658 | 0.87 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL4928562 | 0.87 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL4882668 | 0.87 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2KMT2AHTT | |
| SCHEMBL5715919 | 0.82 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | BIOLIPOX AB (SE) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227787-A1 | Use of New Lipoxygenase Inhibitors | ALOX15, ALOX15B, ALOX12 | NPC1 2644/4885RAB9A 3811/4885NLRP3 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.