SCHEMBL4882948

SCHEMBL4882948

CCc1ccc(F)c(B(c2c(F)ccc(CC)c2F)c2c(F)ccc(CC)c2F)c1F

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547626 0.77 RIPK1 (0.47) RIPK1
SCHEMBL19196278 0.75 GABRA1 (0.39) RIPK1
SCHEMBL5710670 0.75 TYR (0.38)
SCHEMBL29904512 0.75 TYR (0.38)
SCHEMBL4889184 0.74
SCHEMBL5080974 0.73 CES2 (0.35)
SCHEMBL11967063 0.73 RIPK1 (0.38) RIPK1
SCHEMBL20047130 0.73 RIPK1 (0.34) RIPK1
SCHEMBL12524902 0.71 P2RX7 (0.40) RIPK1
SCHEMBL18671257 0.71 MEP1A (0.49) RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817318-B1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS NIPPON CATALYTIC CHEM IND (JP) 2013-08-28 EP disclosed
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds NIPPON SHOKUBAI CO., LTD. (JP) 2008-06-26 US disclosed
EP-1817318-A1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS Nippon Shokubai Co.,Ltd. (JP) 2007-08-15 EP disclosed
WO-2006080538-A1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS NIPPON SHOKUBAI CO., LTD. (JP) 2006-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds AR, AHR, BCL6 RIPK1 3374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.