SCHEMBL5080974

SCHEMBL5080974

Fc1ccc(F)c(B(c2c(F)ccc(F)c2F)c2c(F)ccc(F)c2F)c1F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
GPR84 Q9NQS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4886918 0.78 ACHE (0.35)
SCHEMBL1364743 0.77 CES2 (0.37) CES2CES1GPR84
SCHEMBL31162440 0.76 ACHE (0.33)
SCHEMBL4889113 0.75 TUBB1 (0.40)
SCHEMBL4882948 0.73 RIPK1 (0.33)
SCHEMBL45430 0.71 CES2 (0.53) CES2CES1GPR84
SCHEMBL183800 0.71 CES2 (0.39) CES2CES1GPR84
SCHEMBL619866 0.71 CA1 (0.36) CES2CES1
SCHEMBL4885889 0.70 L3MBTL1 (0.42)
Ammonia Solution, Strong SCHEMBL3047305 0.68 CES2 (0.50) CES2CES1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314903-B2 Catalyst system for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2008-01-01 US disclosed
US-20060094840-A1 Catalyst system for the polymerization of olefins BASSELL POLLYOLEFINE GMBH (DE) 2006-05-04 US disclosed
EP-1611167-A2 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS Basell Polyolefine GmbH (DE) 2006-01-04 EP disclosed
US-6878786-B2 Process for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2005-04-12 US disclosed
US-6841501-B2 Catalyst system for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-01-11 US disclosed
EP-1173445-B1 ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-06-09 EP disclosed
US-20040030153-A1 Process for the polymerization of olefins EQUISTAR CHEMICALS, LP 2004-02-12 US disclosed
WO-2004005360-A2 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE GMBH (DE) 2004-01-15 WO disclosed
US-20030228976-A1 Catalyst system for the polymerization of olefins RESCONI LUIGI (IT) 2003-12-11 US disclosed
US-6608224-B2 Useful as cocatalysts for polymerizing olefins BASELL POLYOLEFINE GMBH (DE) 2003-08-19 US disclosed
US-20020038036-A1 \"Catalyst system for the polymerization of olefins\ EQUISTAR CHEMICALS, LP 2002-03-28 US disclosed
EP-1173445-A1 ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS Basell Technology Company B.V. (NL) 2002-01-23 EP disclosed
WO-2001062764-A1 ORGANOMETALLIC COMPOUND USEFUL AS COCATALYST FOR POLYMERIZING OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2001-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040030153-A1 Process for the polymerization of olefins MT-CO1, UQCRC1, MT-CO3 CES2 2740/4885CES1 1271/4885GPR84 4108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.