SCHEMBL4883056

SCHEMBL4883056

CC(C)(C)OC(=O)N[C@H](C(=O)N1CCC(NC(=O)c2ccc(F)cc2)CC1)C(C)(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.52
TSHR P16473 3/20 0.49
USP2 O75604 1/20 0.49
MEN1 O00255 5/20 0.48
HDAC4 P56524 1/20 0.46
POLB P06746 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
SLC6A12 P48065 1/20 0.45
TMEM97 Q5BJF2 1/20 0.45
MCHR1 Q99705 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
MAPT P10636 1/20 0.44
HTR1A P08908 1/20 0.44
HTR7 P34969 1/20 0.44
CTSB P07858 1/20 0.44
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44
CTSC P53634 1/20 0.44
KDM5A P29375 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4888091 0.87 EPHX2 (0.55) NPC1RAB9A
SCHEMBL4886950 0.83 MMP13 (0.48) POLBHTR1AHTR7
SCHEMBL4603719 0.82 HDAC4 (0.63) KMT2ATSHRUSP2MEN1HDAC4
SCHEMBL4167585 0.79 NPC1 (0.60) KMT2ATSHRUSP2MEN1HDAC4
SCHEMBL24512806 0.79 NPC1 (0.60) KMT2ATSHRUSP2MEN1HDAC4
Hydrochloric Acid SCHEMBL4884743 0.78 KMT2A (0.58) KMT2ATSHRUSP2MEN1POLB
Hydrochloric Acid SCHEMBL4602043 0.78 KMT2A (0.58) KMT2ATSHRUSP2MEN1POLB
SCHEMBL22928847 0.78 NAMPT (0.64) KMT2AMEN1
SCHEMBL1425012 0.76 KMT2A (0.64) KMT2ATSHRUSP2MEN1POLB
SCHEMBL4880753 0.76 MMP2 (0.50) KMT2ATSHRUSP2MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080234333-A1 Novel Hydroxamic Acid Derivative as Peptide Deformylase Inhibitor and Manufacturing Method Thereof KANG JAE-HOON 2008-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080234333-A1 Novel Hydroxamic Acid Derivative as Peptide Deformylase Inhibitor and Manufacturing Method Thereof PDF, PEPD, DHPS KMT2A 1445/4885TSHR 3586/4885USP2 2250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.