SCHEMBL488382

SCHEMBL488382

Cc1ccc(S(C)(=N)=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.59
CA1 P00915 3/20 0.54
CA2 P00918 3/20 0.54
CA12 O43570 1/20 0.54
CA3 P07451 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
TLR9 Q9NR96 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.50
ALDH1A1 P00352 3/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2C19 P33261 2/20 0.48
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20373238 0.81 GAA (0.62) GAACA1CA2CA12CA3
SCHEMBL12807 0.78 GAA (0.65) GAACA1CA2CA12CA3
SCHEMBL28182477 0.78 GAA (0.65) GAACA1CA2CA12CA3
SCHEMBL2290762 0.77 PTGS2 (0.48) CA1CA2ALDH1A1MMP1MMP2
SCHEMBL17642663 0.77 CA1 (0.46) CA1CA2CA12CA9MMP1
SCHEMBL23145865 0.77 ENPP2 (0.41) GAACA1CA2CA12CA3
SCHEMBL3929345 0.77 TSHR (0.56) GAACA1CA2CA12CA6
SCHEMBL9628601 0.77 CA2 (0.52) GAACA1CA2CA12CA9
SCHEMBL11586425 0.77 GAA (0.56) GAACA1CA2CA12CA3
SCHEMBL19483507 0.77 GAA (0.56) GAACA1CA2CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112390697-B Synthesis method of N-arylselenium/thioethyl sulfoxide imine 成都理工大学 2023-03-10 CN claimed
CN-112390697-A Synthesis method of N-arylselenium/thioethyl sulfoxide imine 成都理工大学 2021-02-23 CN claimed
WO-2025073057-A1 METHODS FOR PREPARING SULFILIMINES AND SULFOXIMINES FROM THIOETHERS USING O-(DIPHENYLPHOSPHINYL)HYDROXYL AMINE (DPPH), AND AMATOXIN ANALOGS PREPARED FROM SUCH METHODS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-04-10 WO disclosed
CN-117305865-A Electrochemical method for preparing N-aroyl sulfoxide imine compound 桂林理工大学 2023-12-29 CN disclosed
WO-2023081841-A1 AKT3 MODULATORS GEORGIAMUNE LLC (US) 2023-05-11 WO disclosed
CN-112390697-B Synthesis method of N-arylselenium/thioethyl sulfoxide imine 成都理工大学 2023-03-10 CN disclosed
CN-114920680-A Synthetic method for N-arylation of NH-sulfoximine under aqueous phase catalysis 新乡市润宇新材料科技有限公司 2022-08-19 CN disclosed
WO-2022135365-A1 DISUBSTITUTED CYCLOPENTANE KINASE INHIBITORS ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) 2022-06-30 WO disclosed
WO-2022111621-A1 AMINOHETEROARYL KINASE INHIBITORS ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) 2022-06-02 WO disclosed
WO-2021225969-A1 IMINO SULFANONE INHIBITORS OF ENPP1 VOLASTRA THERAPEUTICS, INC. (US) 2021-11-11 WO disclosed
WO-2021130638-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2021-07-01 WO disclosed
US-20090186911-A1 SULPHOXIMINE-SUBSTITUTED QUINAZOLINE DERIVATIVES AS IMMUNO-MODULATORS, THEIR PREPARATION AND USE AS MEDICAMENTS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2009-07-23 US disclosed
WO-2008141843-A1 NOVEL SULPHOXIMINE-SUBSTITUTED QUINAZOLINE AND QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-11-27 WO disclosed
US-20060217353-A1 24-sulfoximine vitamin D3 compounds CYTOCHROMA INC. (CA) 2006-09-28 US disclosed
US-7101865-B2 24-sulfoximine vitamin D3 compounds CYTOCHROMA INC. (CA) 2006-09-05 US disclosed
EP-1511725-A1 24-SULFOXIMINE VITAMIN D sb 3 /sb COMPOUNDS Johns Hopkins University (US) 2005-03-09 EP disclosed
US-20040038949-A1 24-sulfoximine vitamin D3 compounds JOHNS HOPKINS UNIVERSITY 2004-02-26 US disclosed
WO-2003106411-A1 24-SULFOXIMINE VITAMIN D3 COMPOUNDS JOHNS HOPKINS UNIVERSITY (US) 2003-12-24 WO disclosed
US-4556413-A POSTEMERGENCE AND PREEMERGENCE HERBICIDES HOFFMANN-LA ROCHE INC. (US) 1985-12-03 US disclosed
EP-0109575-A2 Benzoic-acid derivatives, process and means for its production F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038949-A1 24-sulfoximine vitamin D3 compounds CYP24A1, CYP2R1, CYP27B1 GAA 2327/4885CA1 3379/4885CA2 2871/4885
US-20060217353-A1 24-sulfoximine vitamin D3 compounds CYP24A1, CYP2R1, CYP27B1 GAA 2265/4885CA1 3533/4885CA2 3149/4885
US-20090186911-A1 SULPHOXIMINE-SUBSTITUTED QUINAZOLINE DERIVATIVES AS IMMUNO-MODULATORS, THEIR PREPARATION AND USE AS MEDICAMENTS IFNG, TPMT, IRF3 GAA 1574/4885CA1 3700/4885CA2 3431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.