SCHEMBL4885339

SCHEMBL4885339

Cn1cc(C(=O)O)c(C(=O)Nc2ccc(Cl)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
POLB P06746 1/20 0.52
P2RX1 P51575 1/20 0.50
RAB9A P51151 3/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPK1 P28482 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NPC1 O15118 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP2D6 P10635 1/20 0.49
AURKA O14965 4/20 0.48
GRIK1 P39086 1/20 0.47
NR3C1 P04150 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7820643 0.77 ALDH1A1 (0.76) LMNAP2RX1MAPTMEN1KMT2A
SCHEMBL12700212 0.76 SORT1 (0.58) LMNAP2RX1RAB9AMAPTMEN1
SCHEMBL8256342 0.75 RAB9A (0.45) LMNAPOLBRAB9AMAPTMEN1
SCHEMBL9044381 0.74 DHODH (0.69) LMNAP2RX1RAB9AMAPTKMT2A
SCHEMBL69773 0.73 NOTUM (0.44) POLBMAPTMEN1KMT2ACYP1A2
SCHEMBL21914835 0.72 P2RX1 (0.62) LMNAP2RX1RAB9AKMT2AMAPK1
SCHEMBL25381106 0.72 MAPT (0.52) LMNAPOLBP2RX1RAB9AMAPT
SCHEMBL11053580 0.72 P2RX1 (0.50) LMNAP2RX1RAB9AMAPTMEN1
SCHEMBL31006433 0.72 NPC1 (0.52) LMNAPOLBRAB9AMAPTMEN1
SCHEMBL12598078 0.70 HDAC8 (0.72) RAB9AMAPTMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080214533-A1 Cyclic Iminocarbamates And Their Use BAYER HEALTHCARE AG (DE) 2008-09-04 US disclosed
US-20080214533-A1 Cyclic Iminocarbamates And Their Use BAYER HEALTHCARE AG (DE) 2008-09-04 US disclosed
US-20080214533-A1 Cyclic Iminocarbamates And Their Use BAYER HEALTHCARE AG (DE) 2008-09-04 US disclosed
WO-2006058630-A1 CYCLIC IMINOCARBAMATES AND USE THEREOF BAYER HEALTHCARE AG (DE) 2006-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080214533-A1 Cyclic Iminocarbamates And Their Use F2, UQCRB, F12 LMNA 66/4885POLB 433/4885P2RX1 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.