SCHEMBL4886485

SCHEMBL4886485

CCC(N)(CC)CC.CS(=O)(=O)O

nearest known ligand 0.35

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.35
CA1 P00915 4/20 0.33
TSHR P16473 1/20 0.33
NT5E P21589 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
TP53 P04637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
THRB P10828 1/20 0.31
LMNA P02545 2/20 0.30
SLC6A6 P31641 1/20 0.30
CYP2C19 P33261 1/20 0.30
BLM P54132 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL17102581 0.90 CA5A (0.40) CA2CA1TSHRNT5ECA4
SCHEMBL699902 0.85 CA2 (0.33) CA2CA1TSHRNT5ECA4
Hydrochloric Acid SCHEMBL27543557 0.80 CA2 (0.30) CA2
Trifluoromethanesulfonic Acid SCHEMBL6830099 0.80 CA1 (0.36) CA2CA1CA7ALDH1A1
SCHEMBL4411396 0.80 CA2 (0.36) CA2CA1TSHR
SCHEMBL44443 0.79
Tromethamine SCHEMBL11143695 0.79 MEN1 (0.59) CA2CA1TSHRNT5ECA4
Bicarbonate SCHEMBL4357750 0.78 MEN1 (0.42) CA2CA1CA9MEN1KMT2A
SCHEMBL17456428 0.76 CA1 (0.44) CA2CA1TP53
Alcohol SCHEMBL239042 0.76 TSHR (0.46) TSHRMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080033209-A1 Method For High-Purity Quaternary Ammonium Compounds BASF AKTIENGSELLSCHAFT (DE) 2008-02-07 US disclosed
US-20080009633-A1 Method for Producing High-Purity Quaternary Ammonium Compounds BASF AKTIENGESELLSCHAFT (DE) 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080033209-A1 Method For High-Purity Quaternary Ammonium Compounds ATL3, SMYD3, SP1 CA2 1027/4885CA1 1878/4885TSHR 3940/4885
US-20080009633-A1 Method for Producing High-Purity Quaternary Ammonium Compounds SP1, EIF3A, EIF3H CA2 346/4885CA1 613/4885TSHR 2980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.