Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879857 | 0.86 | L3MBTL1 (0.47) | L3MBTL1KMT2ACHEK1EPHX2NR1H4 | |
| SCHEMBL5227021 | 0.81 | PTPRZ1 (0.38) | L3MBTL1EPHX2NR1H4PTPN1PTPRZ1 | |
| SCHEMBL14026437 | 0.81 | PYCR1 (0.43) | L3MBTL1EPHX2NR1H4PTPN1PTPRZ1 | |
| SCHEMBL6785236 | 0.79 | L3MBTL1 (0.45) | L3MBTL1KMT2ACHEK1EPHX2NR1H4 | |
| SCHEMBL4882424 | 0.76 | ATM (0.53) | L3MBTL1KMT2AGAAALDH1A1MAPK1 | |
| SCHEMBL4877710 | 0.76 | LOXL2 (0.40) | EPHX2NR1H4PTPRZ1KDM4E | |
| SCHEMBL5191785 | 0.75 | PTPN1 (0.36) | L3MBTL1PTPN1PTPRZ1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL4886040 | 0.75 | ATM (0.52) | L3MBTL1KMT2AGAAALDH1A1MAPK1 | |
| SCHEMBL14026441 | 0.75 | MEN1 (0.42) | L3MBTL1KMT2AEPHX2NR1H4PTPN1 | |
| Hydrochloric Acid SCHEMBL4927261 | 0.74 | LOXL2 (0.39) | EPHX2NR1H4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261990-A1 | Novel Pyrimidine Derivatives and their Use | BAYER HEALTHCARE AG (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080261990-A1 | Novel Pyrimidine Derivatives and their Use | BAYER HEALTHCARE AG (DE) | 2008-10-23 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2008-10-16 | — | — | US | disclosed |
| EP-1802594-A1 | NOVEL OXADIAZINONE DERIVATIVES AND USE THEREOF AS PPAR-ALPHA MODULATORS | Bayer HealthCare AG (DE) | 2007-07-04 | — | — | EP | disclosed |
| EP-1742942-A1 | PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| WO-2006040002-A1 | NOVEL OXADIAZINONE DERIVATIVES AND USE THEREOF AS PPAR-ALPHA MODULATORS | BAYER HEALTHCARE AG (DE) | 2006-04-20 | — | — | WO | disclosed |
| WO-2005097784-A1 | PHENYLTHIOACETIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2005-10-20 | — | — | WO | disclosed |
| US-20040176445-A1 | Propionic acid derivatives | BAYER PHARMACEUTICALS CORPORATION | 2004-09-09 | — | — | US | disclosed |
| US-6750236-B2 | CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | disclosed |
| US-20030187041-A1 | Propionic acid derivatives | URBAHNS KLAUS (DE) | 2003-10-02 | — | — | US | disclosed |
| EP-1328508-A2 | PROPIONIC ACID DERIVATIVES WITH PPAR-ALPHA ACTIVATING PROPERTIES | Bayer Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-6548538-B2 | Potent peroxisome proliferator activated receptor (PPAR)-alpha-activating compounds; propionic acid 2-subsituted with an N-(phenylaminocarbonylalkyl), N-(2-furanylmethyl)aminoalkylphenyl group | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-15 | — | — | US | disclosed |
| US-20030032671-A1 | Propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-13 | — | — | US | disclosed |
| WO-2002028821-A2 | PROPIONIC ACID DERIVATIVES WITH PPAR-ALPHA ACTIVATING PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187041-A1 | Propionic acid derivatives | PPARA, PPARD, PPARG | L3MBTL1 4341/4885KMT2A 3323/4885CHEK1 4776/4885 |
| US-20030032671-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | L3MBTL1 4392/4885KMT2A 4215/4885CHEK1 4667/4885 |
| US-20080255202-A1 | Phenylthioacetic Acid Derivatives and Use Thereof | PAH, TST, MPST | L3MBTL1 1702/4885KMT2A 2353/4885CHEK1 3788/4885 |
| US-20040176445-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | L3MBTL1 4392/4885KMT2A 4215/4885CHEK1 4667/4885 |
| US-20080261990-A1 | Novel Pyrimidine Derivatives and their Use | TYMS, TYMP, UMPS | L3MBTL1 2949/4885KMT2A 2985/4885CHEK1 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.