Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884311 | 0.86 | KDM4E (0.48) | ALDH1A1NPSR1KDM4EL3MBTL1LMNA | |
| SCHEMBL4887023 | 0.85 | GABRP (0.51) | ALDH1A1NPSR1CCKBRKDM4EHSD17B10 | |
| SCHEMBL14087736 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1NPSR1CCKBRKDM4EHSD17B10 | |
| SCHEMBL4889261 | 0.80 | LMNA (0.46) | ALDH1A1CCKBRKDM4ELMNATP53 | |
| SCHEMBL4883870 | 0.80 | ALDH1A1 (0.48) | ALDH1A1NPSR1CCKBRKDM4EHSD17B10 | |
| SCHEMBL4894071 | 0.79 | ALDH1A1 (0.46) | ALDH1A1NPSR1CCKBRKDM4EHSD17B10 | |
| SCHEMBL14087779 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NPSR1CCKBRKDM4EHSD17B10 | |
| SCHEMBL4886951 | 0.78 | ALDH1A1 (0.43) | ALDH1A1NPSR1CCKBRKDM4EHSD17B10 | |
| SCHEMBL4886934 | 0.78 | ALDH1A1 (0.43) | ALDH1A1NPSR1CCKBRKDM4EHSD17B10 | |
| SCHEMBL4889268 | 0.78 | LMNA (0.47) | ALDH1A1NPSR1CCKBRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | ALDH1A1 276/4885NPSR1 2465/4885CCKBR 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.