Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.51 |
| ▸ | GABRD | O14764 | 2/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.51 |
| ▸ | GABRE | P78334 | 2/20 | 0.51 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.51 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.51 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.51 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14087736 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1NPSR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4884321 | 0.86 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL4883870 | 0.85 | ALDH1A1 (0.48) | ALDH1A1NPSR1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL4887010 | 0.85 | ALDH1A1 (0.50) | ALDH1A1NPSR1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL4895411 | 0.84 | ALDH1A1 (0.45) | ALDH1A1NPSR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4894181 | 0.82 | ALDH1A1 (0.46) | ALDH1A1NPSR1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL4896054 | 0.81 | LMNA (0.48) | ALDH1A1NPSR1SMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL4886969 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL4892985 | 0.81 | ALDH1A1 (0.52) | ALDH1A1NPSR1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL4896941 | 0.80 | ALDH1A1 (0.47) | ALDH1A1NPSR1KDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | GABRP 711/4885GABRD 891/4885GABRA1 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.