Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4887155 | 0.90 | L3MBTL1 (0.44) | ALDH1A1KDM4ECNR1CNR2OPRK1 | |
| SCHEMBL4892547 | 0.77 | ALDH1A1 (0.40) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4896093 | 0.76 | KMT2A (0.46) | ALDH1A1KDM4ESMN1; SMN2OPRK1KMT2A | |
| SCHEMBL4889461 | 0.74 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL4887551 | 0.73 | ALDH1A1 (0.43) | SLC6A9ALDH1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL4892647 | 0.72 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL4893181 | 0.68 | THRB (0.43) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4882730 | 0.67 | THRB (0.42) | ALDH1A1KDM4EKMT2AMEN1NPSR1 | |
| SCHEMBL4887134 | 0.65 | HPGD (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2APKM | |
| SCHEMBL8675410 | 0.64 | KMT2A (0.53) | ALDH1A1CNR1OPRK1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | SLC6A9 2208/4885ALDH1A1 276/4885KDM4E 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.