Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889461 | 0.85 | KDM4E (0.44) | KDM4EKMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL4896093 | 0.84 | KMT2A (0.46) | KDM4EKMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL4887155 | 0.82 | L3MBTL1 (0.44) | KDM4EKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4882730 | 0.79 | THRB (0.42) | KDM4EKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4887013 | 0.77 | KMT2A (0.40) | KDM4EKMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL4892997 | 0.73 | KMT2A (0.46) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4892456 | 0.73 | THRB (0.38) | KDM4EKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL4886348 | 0.72 | KMT2A (0.48) | KDM4EKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4887565 | 0.72 | SLC6A9 (0.43) | KDM4EKMT2AMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL4893181 | 0.70 | THRB (0.43) | KDM4EKMT2AMEN1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | KDM4E 2519/4885KMT2A 2650/4885MEN1 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.