Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 8/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 7/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 7/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | ICMT | O60725 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488881 | 0.82 | S1PR1 (0.41) | KDM4EHTR1DMETLMNACYP2D6 | |
| SCHEMBL487672 | 0.81 | MET (0.54) | MPOMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL488865 | 0.81 | LMNA (0.41) | ALDH1A1KDM4EHTR1DMETLMNA | |
| SCHEMBL27630059 | 0.76 | ICMT (0.41) | MPOMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL488857 | 0.72 | MPO (0.43) | MPOMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL488920 | 0.68 | MPO (0.44) | MPOMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL30452546 | 0.68 | MPO (0.44) | MPOMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL21724167 | 0.66 | MPO (0.68) | MPOMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL27650232 | 0.63 | MPO (0.44) | MPOMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL488007 | 0.63 | MET (0.53) | KDM4EHTR1DMETLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106197-B2 | Aminoheteroaryl compounds as protein kinase inhibitors | PFIZER INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20070072874-A1 | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN, INC. | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072874-A1 | Aminoheteroaryl compounds as protein kinase inhibitors | MET, MAP4K1, MAP4K2 | MPO 4689/4885MEN1 1141/4885ALDH1A1 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.