SCHEMBL4889470

SCHEMBL4889470

CCc1cc(B(c2cc(CC)c(Br)cc2Br)c2cc(CC)c(Br)cc2Br)c(Br)cc1Br

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21884099 0.80 GABRA1 (0.43) GABRA1GABRB2
SCHEMBL10799329 0.78 GABRA1 (0.42) GABRA1GABRB2
SCHEMBL11807767 0.77 GABRA1 (0.46) GABRA1GABRB2
SCHEMBL15788771 0.69 TSHR (0.44) GABRA1GABRB2
SCHEMBL4886989 0.68 LMNA (0.46)
SCHEMBL24456198 0.67 ALOX15 (0.59) GABRA1GABRB2
SCHEMBL10545243 0.67 POLB (0.38) GABRA1GABRB2
SCHEMBL903950 0.67 GABRA1 (0.37) GABRA1GABRB2
SCHEMBL16736693 0.65 ALOX15 (0.47)
SCHEMBL273226 0.65 ALDH1A1 (0.38) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817318-B1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS NIPPON CATALYTIC CHEM IND (JP) 2013-08-28 EP disclosed
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds NIPPON SHOKUBAI CO., LTD. (JP) 2008-06-26 US disclosed
EP-1817318-A1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS Nippon Shokubai Co.,Ltd. (JP) 2007-08-15 EP disclosed
WO-2006080538-A1 STABILIZING METHOD AND STABILIZED COMPOSITION FOR ARYL BORON COMPOUNDS NIPPON SHOKUBAI CO., LTD. (JP) 2006-08-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154065-A1 Stabilizing Method and Stabilized Composition for Aryl Boron Compounds AR, AHR, BCL6 GABRA1 2034/4885GABRB2 2521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.