Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596709 | 0.92 | CYP11B1 (0.47) | CYP11B1CYP11B2CHEK1POLBALDH1A1 | |
| SCHEMBL4596411 | 0.85 | CYP11B1 (0.51) | CYP11B1CYP11B2POLBMAPTALDH1A1 | |
| SCHEMBL4596717 | 0.84 | CYP11B1 (0.45) | CYP11B1CYP11B2CHEK1POLBMAPT | |
| SCHEMBL3903976 | 0.79 | KIF11 (0.51) | CHEK1MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL19175209 | 0.78 | MASP2 (0.51) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL3484477 | 0.77 | ALDH1A1 (0.52) | MAPTALDH1A1PRSS1NPC1RAB9A | |
| SCHEMBL23226619 | 0.77 | PSEN1 (0.40) | POLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4596863 | 0.76 | TTR (0.43) | MAPTALDH1A1CYP3A4PTGES | |
| SCHEMBL30931064 | 0.74 | NPC1 (0.46) | CYP11B1CYP11B2CHEK1MAPTALDH1A1 | |
| SCHEMBL29182853 | 0.74 | NPC1 (0.46) | CYP11B1CYP11B2CHEK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | CYP11B1 780/4885CYP11B2 1046/4885CHEK1 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.