Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | KIF11 | P52732 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4891667 | 0.77 | HDAC2 (0.47) | HDAC2KIF11HDAC1HDAC3PTGS1 | |
| SCHEMBL4898792 | 0.73 | KIF11 (0.48) | HDAC2KIF11HDAC1 | |
| SCHEMBL3901609 | 0.71 | KIF11 (0.50) | HDAC2KIF11 | |
| SCHEMBL5521041 | 0.67 | KIF11 (0.71) | KIF11 | |
| SCHEMBL4659870 | 0.65 | KIF11 (0.56) | KIF11TRPV1 | |
| SCHEMBL5433350 | 0.64 | KIF11 (0.78) | HDAC2KIF11PTGS1AAK1 | |
| SCHEMBL4044366 | 0.64 | MEN1 (0.45) | KIF11 | |
| SCHEMBL7388602 | 0.63 | ALDH1A1 (0.47) | HDAC1 | |
| SCHEMBL5937215 | 0.62 | RXRA (0.50) | KIF11 | |
| SCHEMBL11874548 | 0.61 | ALDH1A1 (0.52) | HDAC2KIF11HDAC1HDAC3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ADAMS NICHOLAS D | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176830-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | HDAC2 1216/4885KIF11 562/4885HDAC1 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.