Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BCL3 | P20749 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886340 | 0.81 | TSHR (0.51) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL4893717 | 0.79 | L3MBTL1 (0.44) | KMT2AL3MBTL1TP53MAPTALDH1A1 | |
| SCHEMBL4895640 | 0.78 | KDM4E (0.53) | KMT2AMAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL4908569 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1NPSR1KDM4E | |
| SCHEMBL4908582 | 0.78 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1NPSR1KDM4E | |
| SCHEMBL4896113 | 0.77 | MAPK1 (0.52) | L3MBTL1MAPK1ALDH1A1NPSR1KDM4E | |
| SCHEMBL4892539 | 0.75 | GAA (0.43) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL14103291 | 0.73 | TSHR (0.49) | MEN1KMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL4889408 | 0.71 | KMT2A (0.45) | KMT2AMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL4896576 | 0.70 | HTT (0.46) | MEN1KMT2AL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | BLANEY JEFFREY MARK | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200512-A1 | Hepatitis C virus polymerase inhibitors | SSU72, POLR2H, POLR2E | MEN1 3917/4885KMT2A 2650/4885L3MBTL1 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.